Publications by authors named "Prem Blaisie Rajula"

Introduction: To evaluate the enamel abrasion effects of soft, ultra-soft, and nano-bristle toothbrushes using atomic force microscopy (AFM) to guide toothbrush selection for optimal enamel preservation.

Methods: This in vitro study involved 45 extracted human teeth (central and lateral incisors), randomly assigned to three groups (n=15 each): Group I (nano-bristle), Group II (ultra-soft bristle), and Group III (soft bristle). Each specimen underwent 10,000 brushing cycles with a standardized 2 N force to simulate one year of brushing.

View Article and Find Full Text PDF

Background: Periodontal disease is a major contributing factor to tooth loss and can significantly impact overall health. Traditional periodontal therapy typically involves mechanical debridement to remove plaque and calculus, along with the use of antimicrobial agents to reduce bacterial load. Licorice () has a long history of use in traditional medicine for treating various ailments since it contains glycyrrhizin, glabridin, liquiritin, and flavonoids, which possess anti-inflammatory, antioxidant, and antimicrobial activities.

View Article and Find Full Text PDF

Aim To evaluate the biocompatibility of ethanolic extract of (bael/vilvam) leaves with gingival fibroblast cells.  Materials and methods Commercially available bael leaves were used to produce a herbal ethanolic extract using the cold percolation technique. Evaluation of cytotoxicity of the bael leaf extract (BLE) on fibroblast cell line at six different concentrations (200µl/ml, 100µl/ml, 50µl/ml, 25µl/ml, 12.

View Article and Find Full Text PDF

Background: The burgeoning interest in implant and regenerative dental care has led to a notable upsurge in the utilization of regenerative modalities. The intent of the present investigation was to evaluate the osteogenic ability of two different concentrated platelet groups at various concentrations in the human osteosarcoma MG-63 cell line.

Materials And Methods: Blood samples from 21 volunteers with chronic periodontitis were collected which were then centrifuged in accordance with the protocols of Choukroun .

View Article and Find Full Text PDF

Background: , a keystone pathogen and one of the primary pathogens responsible for periodontitis, leads to a chronic inflammatory condition that destroys the periodontal tissues and ultimately results in tooth loss. While conventional non-surgical therapy combined with antibiotics and local drug delivery systems are commonly used to treat periodontitis, certain medicinal herbs have also demonstrated efficacy in its prevention. L.

View Article and Find Full Text PDF

Aim This study aims to assess patient motivation during implant therapy using the newly developed implant treatment motivation scale. Materials and methods A questionnaire study was conducted, consisting of 15 questions designed to explore the motivating factors behind patients' decision to undergo implant therapy. A total of 50 patients about to undergo implant treatment at the Departments of Periodontology, Oral and Maxillofacial Surgery, and Prosthodontics participated in the study.

View Article and Find Full Text PDF

Aim The aim of the study is to assess the cellular viability of various concentrations of different platelet concentrates on pre-osteoblastic MG-63 cells. Materials and methods In this in-vitro experiment, blood samples from 21 individuals with chronic periodontitis were taken and centrifuged according to Choukroun and Miron's protocol to prepare L-PRF and I-PRF, respectively. The methyl thiazolyl tetrazolium (MTT) test was used to determine the viability of 0%, 1%, 2%, 4%, 8%, 10%, and 20% concentrations of L-PRF and I-PRF on MG-63 cells.

View Article and Find Full Text PDF
Article Synopsis
  • - The study assessed the effects of vitamin D supplementation alongside scaling and root planing (SRP) on chronic periodontitis patients, measuring various clinical parameters related to oral health and bone mineral density.
  • - Results showed significant improvements in clinical measurements for both groups after six weeks, with vitamin D levels increasing notably in the supplemented group, although baseline vitamin D levels were similar for both groups.
  • - The findings suggest a connection between periodontitis and low bone density, indicating that patients with periodontitis should be evaluated for bone mineral density and possibly supplemented with vitamin D to help mitigate periodontal damage.
View Article and Find Full Text PDF

Context: Laser has been widely accepted as a substitute to traditional periodontal treatment. Only a finite number of studies are available based on the use of diode laser as a supplement to scaling and root planing (SRP) in the reduction of red-complex bacteria.

Aim: This split-mouth study was aimed to determine the clinical and microbiological effects of diode laser as a supplement to SRP.

View Article and Find Full Text PDF