Publications by authors named "Pregenzer M"

Objective: To compare fees for biopsy, treatment procedure, repair, and 2-month follow-up for nonmelanoma skin cancer (NMSC) treatments: electrodesiccation and curettage (ED&C), excision, and Mohs micrographic surgery (MMS).

Methods: A cost comparison of 936 primary NMSCs diagnosed in 1999/2000 at a University affiliated dermatology practice. Clinical data was from medical record review.

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Background: The ACHIEVE (Optimizing the Treatment of Secondary Hyperparathyroidism: A Comparison of Sensipar and Low Dose Vitamin D vs Escalating Doses of Vitamin D Alone) trial evaluated the efficacy of treatment with cinacalcet plus low-dose activated vitamin D analogues (Cinacalcet-D) compared with vitamin D analogues alone (Flex-D) in attaining KDOQI (Kidney Disease Outcomes Quality Initiative) targets for secondary hyperparathyroidism (SHPT). The economic implications of these treatment regimens have not been explored.

Study Design: Economic analysis of SHPT treatment in hemodialysis patients.

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This paper describes a research approach to develop a brain-computer interface (BCI) based on recognition of subject-specific EEG patterns. EEG signals recorded from sensorimotor areas during mental imagination of specific movements are classified on-line and used e.g.

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A new communication channel for severely handicapped people could be opened with a direct brain to computer interface (BCI). Such a system classifies electrical brain signals online. In a series of training sessions, where electroencephalograph (EEG) signals are recorded on the intact scalp, a classifier is trained to discriminate a limited number of different brain states.

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The study focuses on the problems of dimensionality reduction by means of principal component analysis (PCA) in the context of single-trial EEG data classification (i.e. discriminating between imagined left- and right-hand movement).

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Three subjects were asked to imagine either right or left hand movement depending on a visual cue stimulus. The interval between two consecutive imagination tasks was > 10 s. Each subject imagined a total of 160 hand movements in each of 3-4 sessions (training) without feedback and 7-8 sessions with feedback.

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EEGs of 6 normal subjects were recorded during sequences of periodic left or right hand movement. Left or right was indicated by a visual cue. The question posed was: 'Is it possible to move a cursor on a monitor to the right or left side using the EEG signals for cursor control?' For this purpose the EEG during performance of hand movement was analyzed and classified on-line.

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Several laboratories around the world have recently started to investigate EEG-based brain computer interface (BCI) systems in order to create a new communication channel for subjects with severe motor impairments. The present paper describes an initial evaluation of 64-channel EEG data recorded while subjects used one EEG channel over the left sensorimotor area to control on-line vertical cursor movement. Targets were given at the top or bottom of a computer screen.

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It is well known that mu and central beta rhythms start to desynchronize > 1 s before active hand or finger movement. To investigate whether the same cortical areas are involved in desynchronization of mu and central beta rhythms, 56-channel EEG recordings were made during right- and left-finger flexions in three normal subjects. The event-related desynchronization (ERD) was quantified in single EEG trials and classified by the Distinction Sensitive Learning Vector Quantization (DSLVQ) algorithm.

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One major question in designing an EEG-based Brain Computer Interface to bypass the normal motor pathways is the selection of proper electrode positions. This study investigates electrode selection with a Distinction Sensitive Learning Vector Quantizer (DSLVQ). DSLVQ is an extended Learning Vector Quantizer (LVQ) which employs a weighted distance function for dynamical scaling and feature selection.

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