Outcomes of extended total mesorectal excision in patients with locally advanced rectal cancer.

Aim: Extended total mesorectal excision (eTME) is a complex procedure involving en bloc resection of the structures surrounding the various quadrants of the rectum. This study, presenting the largest series so far of patients undergoing eTME, aimed to assess the surgical and survival outcomes of patients following treatment with eTME and to compare these outcomes with historical data on pelvic exenteration.

Method: The study is a retrospective review of all patients with locally advanced rectal cancer requiring an eTME (2014-2020).