Publications by authors named "Preetha Rajkumar"
Article Synopsis
- Triple-negative breast cancer (TNBC) currently lacks effective targeted treatments, but the study explores the anti-cancer effects of 2-methoxyestradiol (2ME2), previously shown to affect mammary cancer.
- The research involved testing 2ME2 on TNBC cell lines, revealing that it significantly inhibited cell growth, induced apoptosis, and interrupted the cell cycle, while also reducing cell migration and invasion.
- The findings indicate that 2ME2 alters miRNA expression relevant to cancer growth, suggesting its potential as a powerful treatment option for TNBC by targeting key cancer processes.
Purpose: Hepatitis C virus (HCV) infection is the prevalent risk factor for chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC) worldwide. The association between metabolic syndrome (MetS) and HCV infection has not been studied effectively, particularly among different ethnic/racial groups in the US.
Methods: A retrospective cross-sectional study was conducted using data from the National Health and Nutrition Examination Survey (1999-2014).