Publications by authors named "Preetam Cholli"
We describe a case of a 46-year-old man in Missouri, USA, with newly diagnosed advanced HIV and PCR-confirmed mpox keratitis. The keratitis initially resolved after intravenous tecovirimat and penicillin for suspected ocular syphilis coinfection. Despite a confirmatory negative PCR, he developed relapsed, ipsilateral PCR-positive keratitis and severe ocular mpox requiring corneal transplant.
View Article and Find Full Text PDFChallenges, risks, and opportunities of antiretroviral drugs in women of reproductive potential.
Expert Rev Anti Infect Ther
April 2024
Article Synopsis
- The HIV/AIDS epidemic poses major challenges for women's health, but advancements in antiretroviral therapy have improved their quality of life and reduced risks in reproductive health.
- Despite these improvements, access to and adherence to these treatments remain issues, highlighting the need for more research on the effects of antiretrovirals during pregnancy and breastfeeding.
- Innovative solutions like multipurpose technologies and long-acting medications could help improve treatment adherence and health outcomes for women living with HIV, alongside necessary advancements in drug safety testing.
Article Synopsis
- This study evaluated the connection between self-rated health (SRH) and care outcomes in U.S. adults with HIV, analyzing data from a nationally representative sample of 3,692 individuals.
- The results showed that 72% reported "good or better" SRH, but certain factors like missed appointments, depression and anxiety symptoms, unstable housing, and food insecurity were linked to lower SRH.
- The authors suggest that addressing these non-physical health needs, along with improving mental health and housing stability, could enhance SRH among people living with HIV in the U.S.
People with HIV (PWH) can now enjoy longer, healthier lives due to safe and highly effective antiretroviral therapy (ART), and improved care and prevention strategies. New drug formulations such as long-acting injectables (LAI) may overcome some limitations and issues with oral antiretroviral therapy and strengthen medication adherence. However, challenges and questions remain regarding their use in aging populations.
View Article and Find Full Text PDFArticle Synopsis
- - The review covers the history and spread of mpox, including how it affects public health and different populations.
- - It outlines various prevention strategies and dives into the clinical features and treatment options for mpox, especially in those with advanced HIV.
- - The authors highlight the severity of mpox in individuals with advanced HIV and identify key areas where further research is needed to improve understanding and management of the disease.
Background: Human papillomavirus (HPV) is the primary cause of invasive cervical cancer (ICC). The prevalence of various HPV genotypes, ranging from oncogenically low- to high-risk, may be influenced by geographic and demographic factors, which could have critical implications for the screening and prevention of HPV infection and ICC incidence. However, many technical factors may influence the identification of high-risk genotypes associated with ICC in different populations.
View Article and Find Full Text PDFBackground: The predominant implementation paradigm of electronic health record (EHR) systems in low- and middle-income countries (LMICs) relies on standalone system installations at facilities. This implementation approach exacerbates the digital divide, with facilities in areas with inadequate electrical and network infrastructure often left behind. Mobile health (mHealth) technologies have been implemented to extend the reach of digital health, but these systems largely add to the problem of siloed patient data, with few seamlessly interoperating with the EHR systems that are now scaled nationally in many LMICs.
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- - The study evaluated a "screen-and-treat" strategy for cervical cancer screening in HIV-positive and HIV-negative women in Cameroon, using visual inspections and a high-risk HPV test, with a focus on assessing its feasibility and outcomes over a year.
- - Out of 913 women screened, 5% tested positive for visual inspection, but half of those were false positives, highlighting the need for careful triage to avoid unnecessary treatments, especially as HIV-positive women showed a higher likelihood of having HR-HPV.
- - After a year, nearly half of the women who initially tested HR-HPV-positive cleared the infection, with those living with HIV showing a much higher persistence of infection, suggesting different follow-up protocols may be
Background: Cervical cancer screening is one of the most effective cancer prevention strategies, but most women in Africa have never been screened. In 2007, the Cameroon Baptist Convention Health Services, a large faith-based health care system in Cameroon, initiated the Women's Health Program (WHP) to address this disparity. The WHP provides fee-for-service cervical cancer screening using visual inspection with acetic acid enhanced by digital cervicography (VIA-DC), prioritizing care for women living with HIV/AIDS.
View Article and Find Full Text PDFObjectives: To explore pediatric family perspectives and preferences regarding whiteboard use, as well as recommendations for using whiteboards as tools for patient-centered communication and care.
Methods: Semi-structured interviews were conducted with 29 families in a pediatric urban academic hospital inpatient surgical service, exploring whiteboard experiences and suggestions. Parent responses were manually recorded during interviews.