The effect of aging on mast cell density in human skin: a comparative analysis of photoexposed and photoprotected regions.

Background: Mast cells are mononuclear cells originating from bone marrow. They produce various biologically active substances, which allow them to actively participate in immune and inflammatory processes associated with intrinsic and extrinsic skin aging. This research focused on distribution and density of mast cells in healthy skin in different stages of skin aging.

The structural characteristics of photoaging in mice caused by the effects of ultraviolet A radiation.

Background: Due to its deep penetration into the dermis, ultraviolet A (UVA) radiation is considered a primary factor in skin photoaging. The aim of this study is to use a qualitative and quantitative analysis to determine the structural parameters of skin photoaging in mice exposed to UVA radiation, with or without the application of a photoprotective cream.

Material And Methods: The experiment consisted of the radiation of female BALBc mice in a solarium by UVA rays, up to total dosages of 7800 J/cm² and 12500J/cm².

Quantitative morphometric analysis of the myenteric nervous plexus ganglion structures along the human digestive tract.

Background/aim: All the functions of the digestive system are controlled, guided and initiated by the autonomic nervous system. A special part of this system placed in the wall of the gastrointestinal tract is known as the enteric or metasympathetic nervous system. The aim of this study was to analyse myenteric nervous plexus in different parts of the digestive tract.

Age-related structural changes in the myenteric nervous plexus ganglion along the anterior wall of the proximal human duodenum--a morphometric analysis.

Background/aim: Aging is one of the most complex biological processes which probably affect structure and function of the enteric nerve system. However, there is not much available information on this topic, particularly in humans. The aim of this study was to investigate the influence of aging on the structure of the myenteric ganglia in the anterior wall of the human proximal duodenum.

Asymmetries in numerical density of pyramidal neurons in the fifth layer of the human posterior parietal cortex.

Background/aim: Both superior parietal lobule (SPL) of dorsolateral hemispheric surface and precuneus (PEC) of medial surface are the parts of posterior parietal cortex. The aim of this study was to determine the numerical density (Nv) of pyramidal neurons in the layer V of SPL and PEC and their potential differences.

Methods: From 20 (40 hemispheres) formaline fixed human brains (both sexes; 27- 65 years) tissue blocks from SPL and PEC from the left and right hemisphere were used.