Publications by authors named "Prayag Pershad"

Article Synopsis
  • Osteoarthritis varies between individuals, and the study aimed to explore how sex and specific knee injuries influence cellular processes and repair mechanisms related to post-traumatic osteoarthritis (PTOA).
  • Researchers examined synovial fluid (SF) from 33 knee surgery patients and analyzed metabolites with blood samples, focusing on differences linked to sex and types of knee injuries (ligament, meniscal, or both).
  • Results indicated distinct metabolic changes based on injury type and sex, with specific metabolites like cervonyl carnitine differing in concentration, highlighting the need for further research on how these factors impact PTOA development in men and women.
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Background: Post-traumatic osteoarthritis (PTOA) is caused by knee injuries like anterior cruciate ligament (ACL) injuries. Often, ACL injuries are accompanied by damage to other tissues and structures within the knee including the meniscus. Both are known to cause PTOA but underlying cellular mechanisms driving disease remain unknown.

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Background: Enhanced recovery after surgery (ERAS) protocols in orthopaedic surgery have garnered significant focus due to their ability to control pain adequately in the immediate postoperative window, allowing for earlier mobilization, shorter hospital stays, and fewer complications. Virginia Commonwealth University created a multimodal pain management approach in which patients receive a preoperative femoral nerve block followed by periarticular intraoperative local injection anesthesia consisting of bupivacaine, ketamine, and ketorolac.

Hypothesis: We hypothesized that implementation of the ERAS protocol will decrease postoperative pain scores, decrease recovery time in the postanesthesia care unit (PACU), and decrease opioid use in anterior cruciate ligament (ACL) reconstruction.

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is a rarely reported cause of prosthetic joint infections. This current case report is of a patient from Trinidad, with a history of a right total knee replacement (TKR), who underwent a successful two-stage revision due to a periprosthetic joint infection (PJI). This case report offers a unique treatment plan to successfully treat periprosthetic joint infections and emphasizes the importance of obtaining an accurate travel history.

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Anatomic total shoulder arthroplasty (aTSA) and reverse shoulder arthroplasty (RSA) are increasingly common, with volume projected to increase over 90% by the year 2025. Therefore, it is critical to understand the expected longevity of aTSA using modern implants and techniques, rates of conversion to RSA, and most common indications for conversion if surgeons are to properly diagnose and treat patients. A retrospective review was conducted of 800 patients who had undergone aTSA, RSA, or hemiarthroplasty (HA) between 2015 and 2019 at a tertiary-care academic medical center.

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