Colorectal Cancer in India: An Audit from a Tertiary Center in a Low Prevalence Area.

Colorectal cancer (CRC) is a common cancer worldwide with a low reported incidence in India. There is significant geographical variation in the incidence rates, and the presentation may also vary. There are few studies evaluating the clinical profile of CRC in Indian patients.

Symptomatic improvement with gluten restriction in irritable bowel syndrome: a prospective, randomized, double blinded placebo controlled trial.

Background/aims: The existence of non-celiac gluten sensitivity has been debated. Indeed, the intestinal and extra-intestinal symptoms of many patients with irritable bowel syndrome (IBS) but without celiac disease or wheat allergy have been shown to improve on a gluten-free diet. Therefore, this study set out to evaluate the effects of gluten on IBS symptoms.

Abdominal Tuberculosis.

Abdomen is involved in 11% of patients with extra-pulmonary tuberculosis; The most common site of involvement is the ileocaecal region, other locations of involvement, in order of descending frequency, are the ascending colon, jejunum, appendix, duodenum, stomach, oesophagus, sigmoid colon, and rectum. Apart from the basic work up, Investigations like CT scan, EUS, Capsule endoscopy, Balloon enteroscopy, Ascitic fluid ADA, TB-PCR, GeneXpert, Laproscopy are being increasingly used to diagnose tuberculosis.Therapy with standard antituberculous drugs is usually highly effective for intestinal TB.

Changing clinical profile and factors associated with liver enzyme abnormalities among HIV-infected persons.

The spectrum of liver disease among HIV-infected patients is changing. In the era of antiretroviral therapy, opportunistic infections are diminishing and deranged liver function appears to be due usually to drug-induced liver injury, alcohol, non-alcoholic steatohepatitis (NASH) or chronic hepatitis B. To test this hypothesis, 98 HIV-positive patients with deranged liver function were compared with matched HIV-positive patients with normal liver function and likewise matched HIV-negative patients with normal liver function tests.

An Interesting Case of Non-Resolving Hepatogastric Fistula - An Unseen Cause.

Hepatic tuberculosis presents one of the rare forms of extra-pulmonary tuberculosis. It is usually secondary to infection in the lung or the gut. Tuberculous liver abscess is the rarer manifestation even in endemic areas of Mycobacterium tuberculosis.

Killian-Jamieson Diverticulum: Cervical Oesophageal Diverticulum.

Killian-Jamieson (K-J) diverticulum is an outpouching from the lateral wall of the proximal cervical oesophagus and is less commonly encountered compared to Zenker’s diverticulum (ZD). These diverticulae arise between the fibers of the cricopharyngeus muscle superiorly and longitudinal muscle of the oesophagus inferiorly. In this report we present a case of a symptomatic Killian Jamieson diverticulum and review the clinical presentation, differential diagnosis and radiological findings that distinguish it from the more common Zenker’s diverticulum.

Early atherosclerosis in ulcerative colitis: cross-sectional case-control study.

Objective: To study the extent of early atherosclerosis in ulcerative colitis (UC) patients by measuring carotid intima-media thickness (CIMT) and the correlation between CIMT, serum homocysteine level and homeostasis model assessment-insulin resistance (HOMA-IR) in UC.

Methods: We studied 60 UC patients and 60 healthy controls. Individuals with risk factors for atherosclerosis were excluded from the study.

Unusual complication of amebic liver abscess: Hepatogastric fistula.

Amebic liver abscess is a parasitic disease which is often encountered in tropical countries. A hepatogastric fistula secondary to an amebic liver abscess is a rare complication of this disease and there are only a handful of reported cases in literature. Here we present a case of an amebic liver abscess which was complicated with the development of a hepatogastric fistula.

Dieulafoy disease of stomach--an uncommon cause of gastrointestinal system bleeding.

Dieulafoy disease is an uncommon cause of gastrointestinal system bleeding. It is characterised by bleeding from abnormal submucosal arteriole. Endoscopic therapy and surgery are the preferred treatment option for this lesion.

A Case of Synchronous Squamous Cell Carcinoma in the Esophagus and Stomach: A Rare Duo.

Synchronous squamous cell esophageal and squamous cell gastric cancer is a rare duo. A 48-year-old male visited our hospital with a history of dysphagia and melena and was diagnosed with synchronous esophageal and gastric cancer by endoscopy and histopathology. We report a case of a synchronous cancer that was successfully treated by chemotherapy followed by surgery.