Poor asthma control in obese children may be overestimated because of enhanced perception of dyspnea.

Background: Although studies in adults have shown a non-TH2 obese asthma phenotype, whether a similar phenotype exists in children is unclear.

Objective: We hypothesized that asthmatic children with obesity, defined as a body mass index above the 95th percentile for age and sex, would have poorer asthma control as well as decreased quality of life, increased health care utilization, and decreased pulmonary function measures as a function of increased TH1 versus TH2 polarization.

Methods: This study involved a post hoc analysis of cross sectional data from 269 children 6 to 17 years of age enrolled in the National Heart, Lung, and Blood Institute Severe Asthma Research Program.

Budd-Chiari syndrome--a case report.

A 21year old male presented with abdominal pain for 2 months and abdominal distension and swelling of lower limbs for 1 month. Ultrasonography of abdomen showing coarse echotexture of liver and intraluminal filling defect of inferior vena cava (IVC) and CT scan confirming the USG finding and showing enlarged caudate lobe of liver and thrombus in proximal IVC suggested the possibility of Budd-Chiari syndrome. Confirmation of diagnosis was done by inferior venacavography.