Disorders of Water Balance Following Sellar and Suprasellar Surgeries: Patterns, Determinants and Utility of Quantitative Analysis.

Background And Objective: The primary objective of this study was to evaluate the application of principles of quantitative analysis to assess disorders of water balance following surgeries for sellar and suprasellar masses and also to investigate potential factors influencing the occurrence and course of these disorders.

Materials And Methods: A total of 36 consecutive adult patients who underwent surgery for sellar and suprasellar masses between 2014 and 2015 were prospectively followed up in this observational study. Twenty-one patients had complete laboratory parameter records for quantitative analysis.

Permanent neonatal diabetes mellitus due to a C96Y heterozygous mutation in the insulin gene. A case report.

Context: Neonatal diabetes is a rare disorder with an incidence of 1 in 215,000-500,000 live births with 50% of them having permanent neonatal diabetes mellitus.

Case Report: We present a case of permanent neonatal diabetes mellitus due to a C96Y (c.287G>A; p.