Evidence for Stress-induced Bleeding in a Patient with von Willebrand Factor Deficiency.

Literature reveals that psychological stress is related to hemostatic mechanisms and that excess stress can lead to prothrombotic events. Patients with chronic bleeding disorders report increased levels of subjective distress. The psychobiological link between stress and bleeding tendencies is rarely investigated when compared to the wealth of the studies on stress and clotting mechanisms.

Low-Dose Mirtazapine-Induced Nightmares Necessitating its Discontinuation in a Young Adult Female.

Mirtazapine is a novel tetracyclic antidepressant which enhances noradrenergic and serotonergic transmission by blocking central α2-adrenergic auto- and hetero-receptors. Due to favorable safety and adverse effect profile, it is often viewed as a promising agent for treatment of depression. Particularly, its anxiolytic and sleep-improving properties have led to its favorable positioning for the management of depression with insomnia.

Role of Exclusive Breastfeeding in Conferring Protection in Children At-Risk for Autism Spectrum Disorder: Results from a Sibling Case-control Study.

Background: Gut microflora influences neural development through complex mechanisms. Feeding practices, especially breastfeeding influence gut microbiome and thereby play a pivotal role in immune and neural development. Current understandings of the role of healthy distal gut microflora in the development of immune and neural systems provide insights into immunological mechanisms as one of the possible etiologies in autism spectrum disorder (ASD).