Publications by authors named "Pratiti Banerjee"
Neuromyelitis optica spectrum disorders (NMOSD) are chronic inflammatory diseases of the central nervous system, characterized by autoantibodies against aquaporin-4. The symptoms primarily involve severe optic neuritis and longitudinally extensive transverse myelitis. Although the disease progression is typically relapse-dependent, recent studies revealed retinal neuroaxonal degeneration unrelated to relapse activity, potentially due to anti-aquaporin-4-positive antibodies interacting with retinal glial cells such as Müller cells.
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- - After years of setbacks, complement-targeted therapies are now recognized as effective treatments for various diseases, leading to renewed interest in their potential benefits.
- - The discussion highlights the need for improved diagnostics alongside these therapies, emphasizing the role of complement biomarkers, particularly the human factor H (FH) protein family, in assessing disease risk and treatment responses.
- - The review aims to synthesize current research on circulating levels of FH proteins across different diseases and outlines crucial next steps for integrating these findings into clinical practice.