Synopsis of recent research by authors named "Pratima Rawat"
- Pratima Rawat's recent research focuses on the interplay between HIV-1, human microglia, and inflammatory responses, emphasizing the role of TREM1 in microglial resistance to HIV-induced apoptosis and the mechanisms behind neurocognitive disorders in HIV-infected individuals.
- The findings from her studies reveal that HIV-1 can activate pro-inflammatory pathways through RNA-mediated mechanisms and demonstrates how pharmacological interventions, like IRAK1 inhibition, can mitigate inflammatory responses in the central nervous system.
- Additional research highlights the significance of personalized genomic approaches in understanding neurocognitive impairments in children perinatally infected with HIV and underscores the importance of autophagy and heat shock proteins in HIV replication and pathogenesis.
