Publications by Pratima Krishna

Publications by authors named "Pratima Krishna"

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Advancing age leads to predominance of inhibitory receptor expressing CD4 T cells.

Rudragouda Channappanavar Brandon S Twardy Pratima Krishna Susmit Suvas

Mech Ageing Dev

October 2009

Decline in CD4 T cell function is the hallmark of aging. In this study, we compared the proportion and absolute number of inhibitory receptor expressing splenic CD4 T cells in unprimed young (2 months) and aged (20 months) C57BL/6 mice. Our results showed a predominance of PD-1, ICOS and CTLA-4 expressing conventional and regulatory CD4 T cells in aged mice.

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