Background And Objectives: Chronic viral hepatitis is a major public health challenge. The World Health Organization (WHO) and many national programs have set goals for elimination of viral hepatitis by 2030. Screening, Linkage to care (LTC), and access to treatment are very important steps to eliminate viral hepatitis.
View Article and Find Full Text PDFSynthesis of quinoline-containing spiropyrrolizine was achieved via a 1,3-dipolar cycloaddition reaction of azomethine ylide (generated in situ from ninhydrin and l-proline) and ()-2-styrylquinoline. The synthesized compounds were characterized by H NMR, C NMR, HRMS, and single-crystal XRD analysis. The XRD data revealed that the solid-state structures of the compounds belong to the monoclinic system of the space group 2/ and are stabilized through various weak noncovalent interactions such as C-H···O, C-H···π, and π···π interactions.
View Article and Find Full Text PDFIndian J Dermatol Venereol Leprol
March 2022