Distinct gene expression profiles underlie morphological and etiological differences in pediatric cataracts.

Purpose: Pediatric cataract is a major cause of preventable childhood blindness worldwide. Although genetic mutations or infections have been described in patients, the mechanistic basis of human cataract development remains poorly understood. Therefore, gene expression of structural, developmental, profibrotic, and transcription factors in phenotypically and etiologically distinct forms of pediatric cataracts were evaluated.

Comparative analysis of non-absorbable 10-0 nylon sutures with absorbable 10-0 Vicryl sutures in pediatric cataract surgery.

Purpose: The purpose of the study is to compare the efficiency as well as the rate and type of suture-related complications between 10-0 monofilament nylon (Aurolab Nylon Sutures, double arm, Aurolab) and 10-0 polyglactin 910 sutures (Vicryl, single arm, Aurolab) for pediatric cataract surgery.

Methods: It is a prospective, comparative study performed in children who underwent surgery for congenital or developmental cataract from March 2013 to February 2016. Patients underwent suturing with either nylon or Vicryl in unilateral cases, but in most bilateral surgeries, one eye received Vicryl sutures while the other eye received nylon.

Management of a case of divergent strabismus fixus secondary to a congenital fibrosis of extraocular muscles type 2.

A 17-year-old boy presented with a large exotropia with both eyes fixed in an abduction and upgaze, pupillary involvement since childhood. He had mild optic nerve hypoplasia in the right eye and situs inversus of the retinal vessels in the left optic disc. His ocular motility showed restriction of eye movements in all gazes.

Correlation of Corneal Biomechanical Stiffness With Refractive Error and Ocular Biometry in a Pediatric Population.

Purpose: To assess the correlation between corneal biomechanical stiffness and refractive error (RE) in the pediatric population.

Methods: A total of 733 pediatric eyes were included in the study retrospectively. All eyes underwent corneal tomography (Pentacam), RE assessment, and air-puff deformation (Corvis-ST).

Fixation-linked nondissociated hypotropia: a report of 3 cases.

Fixation-linked hypotropia, or hypotropic dissociated vertical deviation, is a rare but well-defined ocular motility disorder characterized by a slow downward drift of a poor-seeing eye when the other eye is fixating on a distant target. It can be successfully treated with a large recession or recession-resection of the inferior rectus muscle. We report 3 cases of fixation-linked nondissociated hypotropia with unilateral high myopia and amblyopia presenting with intermittent hypotropia of the worse-seeing eye when the dominant eye was fixating on a distant target and a hypertropia of the dominant eye when the poorer-seeing eye was made to fix.