Background: Tramadol hydrochloride (T-HCl) has demonstrated to have a local anesthetic effect similar to lidocaine hydrochloride (L-HCl) when administered locally for minor oral surgical procedures.
Purpose: Our study aimed to compare the anesthetic effect of T-HCl versus L-HCl in maxillary premolar extraction.
Study Design, Setting And Sample: The study is a split-mouth, double-blind randomized clinical trial at the Faculty of Dental Sciences, Ramaiah University of Applied Sciences, Bengaluru, India.