Platelet Indices be a New Biomarker for Periodontal Disease.

Background: Platelets play an important role in inflammation and hemostasis. Periodontitis, a chronic inflammatory disease, is linked to an increase in platelet activation leading to increased risk for atherosclerosis and cardiovascular diseases.

Aim: The aim was to evaluate whether platelet indices (mean platelet volume [MPV], platelet distribution width [PDW], and plateletcrit [PCT]) can be a biomarker for determining the severity of periodontal disease and to assess the relation between platelet indices in patients with periodontitis and healthy controls.

Efficacy of local drug delivery of gel in the management of chronic periodontitis: A clinical study.

Context: Periodontitis is an inflammatory disease of microbial origin. Locally delivered antimicrobials reduce subgingival flora. gel has antimicrobial, antioxidant, anti-inflammatory, and immunostimulant effects.