Publications by authors named "Prathamesh Mahadev Patil"
The surge in spinal cord injuries (SCI) attracted many neurobiologists to explore the underlying complex pathophysiology and to offer better therapeutic outcomes. The multimodal approaches to therapy in SCI have proven to be effective but to a limited extent. The clinical basics involve invasive procedures and limited therapeutic interventions, and most preclinical studies and formulations are yet to be translated due to numerous factors.
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- Delayed wound healing is primarily caused by bacterial infections and ongoing inflammation, necessitating materials with antibacterial, anti-inflammatory, and hemostatic properties for better recovery.
- This study introduces a new biomacromolecule-based scaffold (ArCh) made from a combination of arabinogalactan and chitosan, which is enhanced with Glycyrrhizin and Copper sulfide nanoparticles to improve wound healing effects.
- The results showed that these GACuS ArCh scaffolds excelled in swelling, biodegradation, and biocompatibility, and when subjected to NIR light, they exhibited improved hemostatic and antibacterial properties, indicating their potential in promoting faster tissue regeneration and healing.