[Comparative study on myocardial damage in irradiated for a long time and nonirradiated rats after administration of FCOL].

The trials were made to assess the effect of FCOL (9-alpha-fluorocortisol + Na2HPO4) and the effect of K and Mg asparaginates and their mixtures on the modifications of Ca2+, Na+, and K+ ions and of the K/Na ratio in the myocardium of rats not irradiated or submitted to permanent whole-body irradiation (gamma irradiation with 0.57 Gy per day during 25 days, total accumulated dose 14.25 Gy; the trials were performed 25 days after the irradiation).

Circadian changes of gluconeogenic enzymes in irradiated rats.

The authors studied the effect of whole body irradiation at different times of day on the circadian rhythms of gluconeogenic enzymes. They found that: 1. liver and kidney enzyme activities were highest in the light part of the day and lowest in the middle of the dark part; 2.

Modification of radiation response by K and Mg aspartates in continuously irradiated rats and mice.

Monopotassium D, L-aspartate and monomagnesium D, L-aspartate, both in the solution of 500 mg in 100 ml of drinking water administered prior to, during and after the outset of prolonged continuous irradiation increased the survival of rats and mice and improved neuromuscular coordination and physical ability of mice.

[The effect of graduated radiation doses on the follicular apparatus of the ovaries and the adenohypophysis in sheep].

Gradually increased radiation doses were applied directly to the ovaries of laparotomized ewes. The effect of these doses was studied as exerted on the qualitative and quantitative changes in the follicular apparatus of the ovaries and adenohypophysis of ewes in anoestrus and upon the recovery processes later on after irradiation. The ovaries irradiated with the dose of 4.

Oscillations of serum and tissue lipids in rats X-irradiated at different times of day.

Young male Wistar rats (mean body mass 200 g) adapted to a 12: 12 h light: dark regimen (7 a.m.--7 p.

Gluconeogenesis in lethally X-irradiated rats.

The in vivo incorporation of U-14C-alanine into blood glucose and liver glycogen was measured in rats irradiated with a single whole body lethal dose of X-rays. Changes in gluconeogenic enzyme activities were studied in the liver. Increased incorporation of 14C-alanine into blood glucose and liver glycogen were found after irradiation.

[Recovery of hematopoiesis in mice following a continuous irradiation with a dose rate of 0.957 Gy/d and a total accumulated dose of 19.14 Gy. I. Bone marrow, spleen and thymus gland].

This paper deals with the evaluation of histological changes in the bone marrow, spleen and thymus of mice after continuous irradiation with a dose rate of 0.957 Gy/day and a total accumulated dose of 19.14 Gy.

[Plasma and tissue lipids in rats after a flight on the Kosmos-936 biosatellite].

The content of triglycerides, total cholesterol, phospholipids and nonesterified fatty acids was measured in plasma and tissues of rats flown for 18.5 days on Cosmos-936 in the weightless and centrifuged state. The weightlessness exposure increased lipid fractions in plasma and tissues, and artificial gravity produced a beneficial effect.

Effect of dexamethasone on pituitary-adrenocortical response to acute irradiation stress in rats.

After the irradiation with a lethal dose of 387 mC kg-1 (1500 R) an increase of plasma and adrenal corticosterone concentration was found in male rats (about 250 g body weight) during first 24 h as compared to sham-irradiated animals, the maximum increase being observed at 60 min after irradiation. A second period of corticosterone increase was found at 48 and 72 h. At the same time the adrenal weight increased and severe lesions of gastrointestinal tract were found.

Changes of deoxyribonucleoprotein in the spleen, thymus and liver of rats exposed to weightlessness and artificial gravity aboard the Cosmos biosatellites.

Changes of deoxyribonucleoprotein in the spleen, thymus and liver of rats exposed to weightlessness or artificial gravity on board biosatellites Cosmos 782 and Cosmos 936 after 20 days of flight were investigated. The level of polydeoxyribonucleotides in the spleen and thymus of rats exposed during the flight to weightlessness increased 4-11 hours after landing, suggesting breakdown of a part of the deoxyribonucleoprotein present. The use of artificial gravity prevented this breakdown in the thymus but not in the spleen.

The effect of artificial gravity on plasma and tissue lipids in rats: the Cosmos 936 experiment.

Plasma and tissue lipids in male SPF Wistar rats flown for 18.5 days aboard the Cosmos 936 biosatellite were analyzed. One group of rats was subjected to artificial gravity by use of a centrifuge during the flight.

Metabolic changes after non-lethal x-irradiation of rats. II. Serum and tissue lipids.

Male rats of the Wistar strain were subjected to whole-body X-irradiation with 2.39 Gy (250 R) and after irradiation they were pair-fed with the sham-irradiated control group. One, 6 and 24 h, 2, 3, 7, 14, 21, 28, and 38 days after exposure the animals were sacrificed and examined for serum and some tissue lipids.

Recovery of hematopoiesis in bone marrow of mice after continuous irradiation with dose rate 4.8 Gy/day.

In this paper the morphological changes in mouse bone marrow till day 60 after the termination of continuous irradiation with the dose rate 4.8 Gy/day (480 rad/day) and the total accumulated doses 9.6 Gy (960 rad) and 19.

Metabolic changes after non-lethal x-irradiation of rats. I. Carbohydrates, hormones.

Male rats of the Wistar strain were fasted overnight prior to exposure to single total-body X-ray dose of 2.39 Gy (250 R). Irradiated and sham-irradiated rats were pair-fed for 5 days, in the next period they were fed ad libitum.