Pathogenesis of oral submucous fibrosis.

Data from recent epidemiological studies provide overwhelming evidence that areca nut is the main etiological factor for oral submucous fibrosis (OSF). It is logical to hypothesize that the increased collagen synthesis or reduced collagen degradation is the possible mechanism in the development of the disease. There are numerous biological pathways involved in the above processes and it is likely that the normal regulatory mechanisms are either down regulated or up regulated at different stages of the disease.

Malignant transformation of a potentially low risk lichenoid reaction.

Lichenoid reaction represents a family of oral lesions identical, both clinically and histologically to oral lichen planus. The triggering factor for this lesion varies from medicines to dental materials, usually demonstrating a cause-effect relationship unlike lichen planus. We present a typical case of lichenoid reaction on the buccal mucosa that appeared in response to betel quid which progressed to carcinoma during a follow-up period of 6 months.

Atypical case of periapical adenomatoid odontogenic tumour.

The Adenomatoid Odontogenic Tumour (AOT) is a progressively growing asymptomatic benign non-invasive lesion. A rare subvariant of the extrafollicular type of AOT may mimic periapical disease radiographically. We report a 45-year-old male with a periapical radiolucent lesion affecting maxillary central incisor tooth.

Oral myiasis: a rare entity.

Myiasis is the invasion of tissues and organs of human beings or other vertebrates by fly larvae. This phenomenon is well documented in the skin, especially among animals and people in tropical and subtropical areas.When tissues of the oral cavity are invaded by the parasitic larvae of flies, this condition is called oral myiasis.