Publications by authors named "Prashant J Chaudhari"
Article Synopsis
- * USFDA-approved drugs that block VEGFR2 face issues like drug resistance and heart-related side effects, highlighting the need for safer and more effective treatments.
- * The review discusses recent findings on the structure and function of VEGFR2 inhibitors, including crucial molecular interactions and design requirements for developing new cancer therapies.
Sulfobutylether β-cyclodextrin (SBE-β-CD) is a polyanionic cyclic oligosaccharide that contains glucopyranose units forming a torus ring-like structure. SBE-β-CD is gifted with many favorable properties viz. relatively high solubility (>50 folds compared to β-CD), improved stability, and biocompatibility that praised SBE-β-CD as a smart polymer for drug delivery applications.
View Article and Find Full Text PDFThree crucial anticancer scaffolds, namely indolin-2-one, 1,3,4-thiadiazole, and aziridine, are explored to synthesize virtually screened target molecules based on the c-KIT kinase protein. The stem cell factor receptor c-KIT was selected as target because most U.S.
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