Adult cerebral malaria: prognostic importance of imaging findings and correlation with postmortem findings.

Purpose: To correlate imaging abnormalities, clinical features, and postmortem findings in patients with proved cerebral malaria.

Materials And Methods: Twenty-one patients aged 17-50 years with cerebral malaria consented to undergo transverse nonenhanced (10-mm sections) and contrast material-enhanced (8-mm sections in posterior fossa and 10-mm sections in supratentorial region) CT on admission (n = 21) and on day 10 (n = 6), with thin sections (5 mm) obtained in the area of abnormality. All CT scans were evaluated for diffuse cerebral edema, focal parenchymal abnormalities, and hemorrhage.