Publications by authors named "Prasha Mahabeer"
We reviewed Corynebacterium spp. infection cases reported in South Africa during 2015-2023. We analyzed 84 isolates from 83 patients with C.
View Article and Find Full Text PDFObjectives: Providing country-specific estimates of case fatality and sequelae from bacterial meningitis (BM) is important to evaluate and monitor progress toward the World Health Organization's roadmap to "defeating meningitis by 2030".
Methods: From 2016-2020, GERMS-SA conducted enhanced surveillance at 26 hospitals across South Africa. Episodes of laboratory-confirmed BM due to Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis were included.
Background: Community-acquired Gram-negative Enterobacteriaceae infections in malnourished and HIV-infected hospitalised children are not well documented and are of concern because of increasing antibiotic resistance and limited available treatment options. This study describes the clinical characteristics and outcomes of hospitalised children with positive Enterobacteriaceae cultures.
Method: A retrospective chart review of children with Gram-negative Enterobacteriaceae infections was performed in King Edward VIII Hospital, a referral hospital in Durban, KwaZulu-Natal.
Article Synopsis
- The study focused on the epidemiology of candidemia, a yeast infection in the bloodstream, among children in South Africa from 2012 to 2017, with a significant number of cases in neonates (49%).
- The most common types of Candida identified were C. parapsilosis (42%) and C. albicans (36%), with notable fluconazole resistance in C. parapsilosis (55%).
- Despite high overall mortality rates (38%), infection with C. parapsilosis in neonates was associated with lower mortality compared to other species, indicating a complex relationship between the type of Candida and patient outcomes.
Background: Bacterial infections in HIV-infected children admitted with severe acute malnutrition (SAM) contribute to higher mortality and poorer outcomes. This study describes the spectrum of bacterial infections in antiretroviral treatment (ART)-naïve, HIV-infected children admitted with SAM.
Methods: Between July 2012 and February 2015, 82 children were prospectively enrolled in the King Edward VIII Hospital, Durban.