Publications by authors named "Prasanth Dintakurthi Sree Naga Bala Krishna"
and Studies of β-Sitosterol Nanoparticles as a Potential Therapy for Isoprenaline-Induced Cognitive Impairment in Myocardial Infarction, Targeting Myeloperoxidase.
Partha Saradhi Tallapalli Yennam Dastagiri Reddy Deepak A Yaraguppi Surya Prabha Matangi Ranadheer Reddy Challa Prasanth Dintakurthi Sree Naga Bala Krishna
Pharmaceuticals (Basel)
August 2024
Objective: This study aimed to compare the effects of β-sitosterol nanoparticles (BETNs) and β-sitosterol (BET) on cognitive impairment, oxidative stress, and inflammation in a myocardial infarction (MI) rat model using in silico and in vivo methods.
Methods: β-Sitosterol (BET) and myeloperoxidase (MPO) ligand-receptor binding affinities were evaluated using Autodock Vina for docking and Gromacs for dynamics simulations. BET nanoparticles, prepared via solvent evaporation, had their size confirmed by a nanoparticle analyzer.
Utilizing leaves and roots by effective usage of the bioactive andrographolide and its nanodelivery: investigation of antikindling and antioxidant activities through and studies.
Ramana Baru Venkata Dintakurthi Sree Naga Bala Krishna Prasanth Praveen Kumar Pasala Siva Prasad Panda Vinay Bharadwaj Tatipamula
Front Nutr
May 2023
Article Synopsis
- This study is about using leaves from medicinal plants to reduce waste and find ways to treat brain diseases, focusing on a compound called andrographolide (AG) found in Asian plants.
- Researchers discovered that AG may help with epilepsy by increasing a chemical in the brain called GABA, which helps control brain activity.
- To improve how AG works in the body, scientists created tiny particles (nanoparticles) of AG and tested them to see how well they protect against epilepsy in lab rats.