Publications by authors named "Prasanna Ram"

Article Synopsis
  • A new method has been developed to arylate 2-aryl-2-indazoles using aryl iodides without the need for a photocatalyst, yielding 3,2-diaryl-2-indazoles in good to moderate amounts.
  • Potassium tert-butoxide plays a dual role in this reaction by activating the C-I bond and scavenging the HI byproduct generated during the process.
  • This approach shows great versatility with accommodating various functional groups and has been successfully employed to create liver X receptor agonists and fluorescent probes, marking a significant advancement in the field.
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Laparoscopic radical nephrectomy is the standard of care for T1 renal tumors and nowadays being used for T2 or higher tumors, resulting in higher the conversion rates. To bridge this gap, the hand-assisted laparoscopy (HAL) method was introduced. Even now, in the robotic era, this HAL approach continues to find importance in urology, especially in the most challenging cases, albeit, with a relatively low usage rate due to the cost involved and availability of hand port devices.

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Micropapillary urothelial carcinoma of the renal pelvis is a rare and aggressive variant and poses a diagnostic challenge, especially related to the site and histomorphology of the tumor. A 60-year-old female presented with right pelvic-ureteric junction obstruction and a nonfunctioning right kidney. She underwent a simple right nephrectomy.

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Approximately 5% of children with Wilms tumor present with bilateral disease. The treatment challenge is to achieve a high cure rate while maintaining adequate long-term renal function. We report the feasibility and outcome of nephron sparing surgery in a child with bilateral Wilms tumor who was treated at our institution.

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Involvement of the bladder by colorectal cancer is sufficiently rare to be encountered by an individual surgeon on an infrequent basis. Extirpative procedures for advanced colorectal cancers can involve partial/total bladder resections. In patients without evidence of distant metastatic disease, a reasonable therapeutic effect can be expected when negative surgical margins are obtained.

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