Expert Panel Consensus Recommendations for Allergic Rhinitis in Patients with Asthma in India.

Allergic rhinitis and asthma are commonly coexisting conditions, significantly impacting patient health and quality of life. Despite their interrelation, diagnosing allergic rhinitis in patients with asthma remains challenging, leading to underdiagnosis and suboptimal management. The expert consensus engaged a modified Delphi method involving 29 experts including pulmonologists, ear, nose, and throat surgeons, and allergologists.

Cytological Diagnosis Suggesting Candidal Infection of the Nasolacrimal Duct in an Uncontrolled Diabetic Patient With Gingival Abscess.

In this unique cytology case of a 64-year-old diabetic male who presented with left-sided facial swelling between the ala and lateral canthus of the left eye, conventional fine-needle aspiration cytology (FNAC) was done. FNAC of the swelling showed desquamated epithelial cells from the nasolacrimal duct and abundant proteinaceous material admixed with fungal organisms like that of budding yeast forms, morphologically resembling Candida on May-Grunwald-Giemsa stain. Special stain with periodic acid-Schiff revealed positivity for budding yeast forms.

Hyperglycemia and steroid use increase the risk of rhino-orbito-cerebral mucormycosis regardless of COVID-19 hospitalization: Case-control study, India.

Background: In the ongoing COVID-19 pandemic, an increased incidence of ROCM was noted in India among those infected with COVID. We determined risk factors for rhino-orbito-cerebral mucormycosis (ROCM) post Coronavirus disease 2019 (COVID-19) among those never and ever hospitalized for COVID-19 separately through a multicentric, hospital-based, unmatched case-control study across India.

Methods: We defined cases and controls as those with and without post-COVID ROCM, respectively.

Observational evidence of stratification control of upwelling and pelagic fishery in the eastern Arabian Sea.

Upwelling is a physical phenomenon that occurs globally along the eastern boundary of the ocean and supports pelagic fishery which is an important source of protein for the coastal population. Though upwelling and associated small pelagic fishery along the eastern Arabian Sea (EAS) is known to exist at least for the past six decades, our understanding of the factors controlling them are still elusive. Based on observation and data analysis we hypothesize that upwelling in the EAS during 2017 was modulated by freshwater-induced stratification.

Role of Topical Medication in Prevention of Post-extubation Subglottic Stenosis.

Iatrogenic laryngotracheal injury is the most serious complication of endotracheal intubation since this method of establishing airway was first described by Eugene Bouchut in 1858. Even today, subglottic stenosis is the most dreaded complication of intubation. This animal study is focused on the host tissue response to intubation induced injury resulting in subglottic stenosis and methods to prevent this complication.

Isolation, structural elucidation and antiplasmodial activity of fucosterol compound from brown seaweed, Sargassum linearifolium against malarial parasite Plasmodium falciparum.

The brown seaweed, Sargassum linearifolium (Turner) C. Agardh, 1820 is commonly available along the south-east coast of India. Its compound fucosterol was isolated and confirmed through spectral characterisation and chemical transformation methods.

Fungal necrotizing fasciitis of the head and neck in 3 patients with uncontrolled diabetes.

Necrotizing fasciitis is an uncommon, rapidly progressive soft-tissue infection that is associated with a high incidence of morbidity and mortality. It is usually caused by bacteria and rarely caused by or complicated by a fungus. We report 3 cases of necrotizing fasciitis of the head and neck in patients with uncontrolled diabetes.

Fungal laryngitis in immunocompetent patients.

The diagnosis of fungal laryngitis is often overlooked in immunocompetent patients because it is commonly considered a disease of the immunocompromised. Further confusion is caused by clinical and histological similarity to more common conditions like Leukoplakia. Demonstration of hyperkeratosis particularly if associated with intraepithelial neutrophils on biopsy should trigger a search for fungus using specialized stains.

Biometric study of the internal dimensions of subglottis and upper trachea in adult Indian population.

The anatomy of the larynx and trachea is well described in literature, however the intraluminal dimensions and contour of the subglottis has not been well documented. Subglottis and trachea are dynamic structures and the internal dimensions and contours have been studied only on cadavers or by plain radiograph which has many technical and measurement errors. No data is available about the internal dimensions of the subglottic and trachea in Indian population.

Modified radical mastoidectomy: a relook at the surgical pitfalls.

The primary aim of surgery for cholesteatoma is to eliminate the disease, to produce a safe and dry ear which is self cleansing, modify the anatomy of the tympanomastoid compartment so as to prevent recurrent disease and wherever possible to reconstruct the hearing mechanism. The advances in medical technology and the medical expertise gained over a period of time have greatly influenced the results in cholesteatoma surgery. The aim of the present study was to assess the intraoperative findings during revision mastoid surgery for atticoantral disease and to ascertain the preventable factor that could reduce recurrence.

Role of Montgomery T-tube stent for laryngotracheal stenosis.

Objective: To identify the indications, complications and outcome of patients of LTS managed with Montgomery T-tube stenting and review the current literature about the role of stenting in LTS.

Methods: Retrospective chart reviews of 39 patients of laryngotracheal stenosis managed by T-tube stenting for temporary or definitive treatment during the period 2004-2011 were considered. The data on indications for stenting, type of stent, problems/complications of stenting, duration of stenting, additional intervention and outcome of management were collected, tabulated and analyzed.

Structural and functional diversity of rhizobacteria associated with Rauwolfia spp. across the Western Ghat regions of Karnataka, India.

The present study carried out with denaturing gradient gel electrophoresis of DNA extracted from rhizosphere soils of Rauwolfia spp. collected from Western Ghat (WG) regions of Karnataka indicated that Pseudomonas sp. was prevalently found followed by Methylobacterium sp.

Physical and biological response of the Arabian Sea to tropical cyclone Phyan and its implications.

The response to the tropical cyclone Phyan, which developed in the eastern Arabian Sea during 9-11 November 2009, was rapid cooling of sea surface temperature (SST), enhancement of chlorophyll a and two-fold increase in net primary productivity (NPP). Cooling of SST was immediate in response to the strong wind-mixing, and the subsequent upward Ekman pumping sustained the cooling even after the dissipation of Phyan. The biological response mediated by the upward Ekman pumping driven vertical transport of subsurface nutrient showed a time lag of 3-4 days.

Tracheostomal myiasis: a case report and review of the literature.

"Myiasis" is considered in Hindu mythology as "God's punishment for sinners." It is known to infest live human or animal tissue. Literature abounds with reports of myiasis affecting the nasal cavity, ear, nonhealing ulcers, exophytic malignant growth, and cutaneous tissue.

Nutrient characteristics of the water masses and their seasonal variability in the eastern equatorial Indian Ocean.

Nutrient characteristics of four water masses in the light of their thermohaline properties are examined in the eastern Equatorial Indian Ocean during winter, spring and summer monsoon. The presence of low salinity water mass with "Surface enrichments" of inorganic nutrients was observed relative to 20 m in the mixed layer. Lowest oxygen levels of 19 microM at 3 degrees N in the euphotic zone indicate mixing of low oxygen high salinity Arabian Sea waters with the equatorial Indian Ocean.

Butyrate-induced phosphatase regulates VEGF and angiogenesis via Sp1.

Sp1 is a ubiquitous transcription factor and master regulator of various eukaryotic gene expression. Better understanding of the role of increased Sp1 levels on angiogenic regulation and the regulatory regions of that transcription factor may act as a useful target in 'transcriptional therapy'. At the molecular level, butyrate inhibits Sp1-DNA binding activity by promoting Sp1 protein dephosphorylation in EAT cells.