Publications by authors named "Prasad Rao"

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  • Gut bacterial dysbiosis is linked to serious gastrointestinal diseases, particularly colorectal cancer (CRC), and this study focuses on the lesser-explored gut bacteria changes in colon cancer (CC) patients.
  • Using advanced sequencing techniques, researchers found notable differences in gut bacteria composition between CC patients and healthy controls, indicating a shift in the microbial community.
  • The study identified a rise in low-abundance anaerobic bacteria and a decrease in harmful Klebsiella, suggesting that these changes could provide new insights for diagnostic and treatment strategies for colon cancer.
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  • The study explores copy number variants (CNVs) as significant genetic factors in schizophrenia, focusing on a South Indian population for the first time.
  • Researchers identified 63 different CNVs in 168 schizophrenia patients and 168 controls, noting a higher presence of medium-sized deletions in patients compared to controls.
  • The findings underscore the need for further research in larger samples and suggest that an integrated approach can enhance the identification of CNVs linked to schizophrenia and other mental health disorders.
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  • Benign recurrent aseptic meningitis is a rare condition marked by recurring episodes of aseptic meningitis that resolve on their own, usually within two to seven days.
  • Symptoms include meningeal irritation, fever, and an increase in certain white blood cells (mononuclear cell pleocytosis), and diagnosis comes after ruling out other causes.
  • The condition is often associated with the herpes simplex virus 2 (HSV 2), but it's uncertain whether preventive medication is necessary for affected individuals; the text describes a patient facing her seventh episode.
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Background: Healthcare workers (HCWs) are at increased risk of coronavirus 2019 (COVID-19) infection. Personal protective equipment (PPE) and infection control guidelines help limit transmission. However, poor confidence leads to higher levels of anxiety rates and infection.

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Kicking off on 1 October with the United Nations' International Day of Older Persons (UNIDOP) and concluding on 10 October in conjunction with World Mental Health Day, the OLDER ADULT MENTAL HEALTH AWARENESS WEEK was a brand-new ten-day initiative launched by the International Psychogeriatric Association (IPA). It was focused on raising awareness of the importance of Better Mental Health for Older People with virtual programs from all around the world on each of these ten days. As part of this Awareness Week, the IPA hosted a discussion entitled "Mental healthcare services and advocacy for the older people amidst COVID crisis: Voices from South Asia", organized on October 6, 2021 in conjunction with the World Psychiatric Association (WPA), Indian Psychiatric Society (IPS), Indian Association of Geriatric Mental Health (IAGMH), SAARC Psychiatric Federation (SPF), and the Asian Federation of Psychiatric Associations (AFPA).

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Objectives: Repetitive transcranial magnetic stimulation (rTMS) is used as a therapeutic option for obsessive-compulsive disorder (OCD) in both clinical and research settings. There has been no consensus with regard to target area and other parameters, although 1-Hz rTMS over the supplementary motor area (SMA) is found to be promising. Priming stimulation, which involves high-frequency followed by low-frequency rTMS, has been shown to enhance neural response to low-frequency rTMS.

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  • * An online survey found that nearly half (46.2%) of the 303 health-care workers reported anxiety or depression, with 12.9% exhibiting suicidal behavior.
  • * Female HCWs, those under 30, and those directly caring for COVID-19 patients were particularly vulnerable to higher levels of anxiety and depression, highlighting the urgent need for mental health support and assessment for these workers.
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A recent study showed the association of minor alleles of (T allele) and (T allele) of with schizophrenia (SZ) and suggested their effects on splicing of the transcripts. We performed a replication study using 310 controls and 304 SZ patients and confirmed the association of the homozygous minor allele genotypes with SZ ( = 0.04 for and  = 0.

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Background: The COVID-19 pandemic has led to a complete shut-down of the entire world and almost all the countries are presently in a "lockdown" mode. While the lockdown strategy is an essential step to curb the exponential rise of COVID-19 cases, the impact of the same on mental health is not well known.

Aim: This study aimed to evaluate the psychological impact of lockdown due to COVID-19 pandemic on the general public with an objective to assess the prevalence of depression, anxiety, perceived stress, well-being, and other psychological issues.

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Introduction Annually 80,000 hip fractures are treated at an estimated cost of two billion pounds. The 2011 guidance from the Royal College of Pathologists recommended all specimens where there is fracture through or below the articular surface should be examined to exclude/ identify an underlying cause (pathological fracture). The questions posed in this study are three-fold.

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Copy number variants (CNVs) of 15q11.2 yielded conflicting reports on their association with schizophrenia (SZ), indicating the need for replication studies. Because there are no 15q11.

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Background And Aims: Selection of an appropriate endotracheal tube (ETT) in paediatric patients is a challenging situation. The purpose of this study was to compare whether measurement of subglottic diameter with ultrasound or the age-old little finger width correlates better with the outer diameter (OD) of the ETT used for intubation.

Methods: Following approval from the Institutional Ethics board and a written informed consent from parent or guardian, this prospective observational study was carried out on 60 American Society of Anesthesiologists physical status I and II patients aged 6 months-8 years, scheduled for elective surgery under general anaesthesia requiring oral endotracheal intubation.

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Objective: Multiple factors influence the success of microvascular free flap surgeries. Anaesthesia is an important factor to maximise the success rate of microvascular free flaps both by controlling haemodynamics and improving the perfusion of free vascularised tissue. The debate on the usefulness of regional and general anaesthesia for free tissue transfer is ongoing.

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Borrelia burgdorferi was discovered to be the cause of Lyme disease in 1983, leading to seroassays. The 1994 serodiagnostic testing guidelines predated a full understanding of key B. burgdorferi antigens and have a number of shortcomings.

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Introduction: Undertaking a research project is mandatory for MD Psychiatry trainees. The present study was undertaken to assess the type of research activity being undertaken as part of MD Psychiatry dissertation, and its contribution to national and international literature.

Materials And Methods: Three medical colleges supplied the data about the topic, names of the supervisor and the candidate, collaboration, funding accrued, and publication details of MD-based research carried out between years 2000 and 2010 inclusive; 95 records were collected for the final analysis.

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There is a growing incidence of dementia patients in the community, and with this growth, there is need for rapid, valid, and easily administrable tests for the screening of dementia and mild cognitive impairment in the community. This review looks at the two most commonly used tests in dementia screening, namely, the clock drawing test (CDT) and the mini-mental status examination (MMSE). Both these tests have been used in dementia screening over the past three decades and have been the subject of scrutiny of various studies, reviews, and meta-analysis.

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