Publications by authors named "Prapavat V"

Background And Objective: Apart from the ablation properties at the stapes footplate, the degree of thermic loading in the inner ear is important in determining the suitability of pulsed lasers for stapedotomy. The aim of the study is to compare the thermic effects in the vestibule with different pulsed laser systems.

Study Design/materials And Methods: Temperature increases and heat exchange processes in the fluid (physiological saline) were examined in a calorically and physiologically approximated cochlea model for applying the laser parameters effective in creating footplate perforations.

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In the field of rheumatology, conventional diagnostic methods permit the detection only of advanced stages of the disease, which is at odds with the current clinical demand for the early diagnosis of inflammatory rheumatic diseases. Prompted by current needs, we developed a finger joint phantom that enables the optical and geometrical simulation of an early stage of rheumatoid arthritis (RA). The results presented here form the experimental basis for an evaluation of new RA diagnostic systems based on near infrared light.

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Background And Objective: The aim of the present study was to investigate the tissue ablation capacity of various pulsed lasers at the stapes footplate.

Study Design/materials And Methods: Isolated human stapes and bovine compact-bone platelets were used to determine the effective laser parameters and appropriate application technique for achieving a perforation measuring 500-600 microns in diameter. Of interest were also the shape and quality of the perforations, the reproducibility of the perforation effect, and the thermically altered marginal zones occurring at the footplate.

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Background And Objective: The aim of the present study was to clarify which of the presently available continuous-wave laser systems are best suited for application in stapes surgery.

Study Design/materials And Methods: Isolated human stapes and bovine compact-bone platelets were used to investigate the connections between the parameters of various laser systems and their effects on bone tissue. The purpose was to optimize the laser parameters required to achieve a perforation measuring 500 microns to 600 microns in diameter.

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Background And Objective: This study investigated the feasibility of 850 nm diode laser-induced thermotherapy (LITT), a new procedure providing local hyperthermia and photocoagulation, a minimally invasive treatment of tumors, and other disorders such as benign prostate hyperplasia.

Study Design/material And Methods: An improved fiber optic diffuser inserted through a catheter was used to irradiate prostate, liver, and kidney tissue in-vitro. Experimental results were compared with predictions from mathematical simulations based on measured optical tissue parameters.

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Apart from ablation properties at the stapes footplate, the degree of thermal stress of the inner ear is important when considering the suitability of pulsed lasers for stapedotomy. The aim of the present study was to compare the heating of cochlear structures with presently available pulsed laser systems during stapedotomy under reproducible conditions. Temperature increases and heat-exchange processes were examined in a physiologic model of the cochlea using various laser parameters effective for footplate perforations.

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As a consequence of perforating the footplate during laser stapedotomy, direct radiation to the inner ear will warm perilymph and adjacent structures. To determine the possible thermal dangers to cochlear structures from different laser parameters, heat transport mechanisms, temperature increases and temperature fields were investigated in a model system approximating caloric and physiologic changes in the inner ear. The temperature-time course of local cochlear warming showed a rapid convection-dependent increase that reached a peak at about the end of the laser impulse.

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Endoscopic infrared diaphanoscopy is a method of improving orientation in the nasal cavity during endoscopy-controlled endonasal surgery. The transillumination is expected to facilitate the localisation of the natural passageways between the paranasal sinuses and the nasal cavity during endoscopic procedures. The present study specifies the necessary conditions on the basis of in vitro examinations using an animal model (sheep) and an anatomical preparation of half of the human head.

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The object of the present study was to examine the tissue ablation capacity of various pulsed lasers at the stapes footplate. Isolated human stapes and bovine compact-bone platelets (thickness 90 microns) were used to determine effective laser parameters for achieving a perforation measuring 500 microns to 600 microns in diameter. Apart from achieving the perforation diameters, particular attention was given to the form and quality of the perforations, reproducibility of the perforation effect and the thermally altered border zones occurring at the footplate.

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During stapedotomy, the small dimensions and highly sensitive anatomic structures present require the highest degree of precision and safety. The risk of damage to middle and inner ear structures through manipulation with conventional instruments can be reduced by non-contact perforation of the footplate with the laser beam. The present study was devised to clarify which of the presently available laser systems was best suited for use in stapes surgery and thus represent a significant alternative to conventional stapedotomy.

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