Solitary Fibrous Tumour of the Mesentery: An Uncommon Site for a Rare Tumour.

Solitary fibrous tumour (SFT), a unique spindle-cell neoplasm, was first identified in the pleura and was earlier named as haemangiopericytoma. The origin of SFT is not well established; however, it has recently been described as a mesenchymal neoplasm, probably arising from the ubiquitous dendritic interstitial cells. SFTs are predominantly benign tumours with a low risk of malignant transformation and are commonly seen in the intrathoracic region, seldom involving extrapleural locations.

Clinicopathological Profile of Immunoglobulin A Nephropathy: A Study from Northeast India.

Immunoglobulin A (IgA) nephropathy is the most common primary glomerulopathy, with wide variation in its prevalence as well as clinical symptoms. Among the laboratory parameters, increased serum creatinine (SCr) levels, mean arterial pressure (MAP), and a decreased estimated glomerular filtration rate (eGFR) point toward poorer renal function. The Oxford 2016 scoring system for IgA nephropathy identified various histopathological variables, which serve as indicators of renal outcomes.

Nanostructural Design of ZnO Using an Agro-Waste Extract for a Sustainable Process and Its Photocatalytic Activity.

The use of agro-waste extracts (AWEs) as a sustainable medium for developing cost-effective and ecologically friendly nanomaterials has piqued the interest of current researchers. Herein, waste extracts from papaya barks, banana peels, thumba plants, and snail shells were used for synthesizing ZnO nanostructures via a hydrothermal method, followed by calcination at 400 °C. The crystallinity and pure wurtzite phase formation of ZnO nanostructures were confirmed via X-ray diffraction.

Clinicopathological, Immunological, and Laboratory Parameters of Childhood Lupus Nephritis: A Study from Northeast India.

Lupus nephrtis in children is associated with high morbidity and mortality. The incidence of childhood systemic lupus erythematosus (SLE) ranges from 3.3 to 8.

Xp11.2 Translocation Renal Cell Carcinoma: A Rare Renal Cell Carcinoma.

Translocation-associated renal cell carcinoma (TRCC) is a group of under-recognized malignant renal neoplasms owing to the unavailability of ancillary diagnostic tools and considering the fact that these tumors may histomorphologically mimic a heterogeneous group of neoplasms ranging from benign to malignant ones. Xp11.2 translocation-associated renal cell carcinoma is a disease of the young with a relatively less known prognosis owing to the rarity of such reported neoplasms.

Immunoglobulin A Nephropathy in a SARS-CoV-2-Positive Patient With Coexistent Metabolic Syndrome.

SARS-CoV-2 viral infection though primarily affects the respiratory system, but concurrent renal involvement is been reported in the medical literature. Acute kidney injury (AKI) is a common finding in SARS-CoV-2-positive patients. An isolated case of IgA nephropathy in a SARS-CoV-2 virus-infected patient has been already reported in the medical literature.

High-grade transformation of adenoid cystic carcinoma of parotid gland with isolated intratemporal facial nerve involvement: a case report and literature review.

Background: High-grade transformation Adenoid cystic carcinoma (HGT-AdCC) of the parotid gland is a rare transformation noted in slow growing low grade AdCC. Perineural invasion and spread is an important feature of this tumor. Temporal bone involvement is rare.

Hepatosplenic T Cell Lymphoma: Diagnostic Conundrum.

Hepatosplenic T cell lymphoma (HSTCL) is a very rare and aggressive peripheral T cell lymphoma that comprises less than 1% of Non-Hodgkin lymphomas (NHL). It is derived from cytotoxic T-cells, usually of γδ T cell receptor type, and is characterized by primary extranodal disease with typical sinusoidal infiltration of the liver, spleen and bone marrow by medium-sized lymphoid cells. HSTCL occurs more frequently in immunocompromised patients, especially in those receiving long-term immunosuppressive therapy.

Role of interfacial contact between 2D materials and preselected nanostructures in the degradation of toxic dyes: Multifunctional facets of graphene.

Designing intimate interfacial contact between nanostructures and two-dimensional (2D) materials is highly desirable to influence the movement of generated charge carriers. Nanostructured zinc oxide (ZnO) is a fascinating material with unique optical and electrical properties. 2D reduced graphene oxide (rGO) exhibits semiconductor behaviour with tunable catalytic activity and excellent biocompatibility.

Synthesis, characterization, and photocatalytic activity of ZnO nanoparticles using water extract of waste coconut husk.

The present work reports the use of natural alkaline extract from coconut husk ash as a precipitating agent for metal oxide nanoparticles synthesis. The abundance of KO and KCO in it makes the extract highly basic and could be the alternative source of basic media in the laboratory. In this study, highly photoactive zinc oxide nanoparticles have been synthesized using water extract of waste coconut husk ash in a green approach which is considered as replacement of homogeneous base like NaOH and KOH.

Hemophagocytic Lymphohistiocytosis Secondary to Adult-Onset Still's Disease.

Hemophagocytic lymphohistiocytosis (HLH) is a rare hematological condition resulting from dysregulation of the immune system. This unusual clinical syndrome is characterized by fever, cytopenia, liver dysfunction, increased ferritin level, and evidence of hemophagocytosis in the bone marrow. We report a case of a 21-year-old female who presented with recurrent high-grade fever, transient rash, and polyarthritis who was subsequently diagnosed with adult-onset Still's disease (AOSD) with secondary HLH.

Secondary Hemophagocytic Lymphohistiocytosis in Post-COVID-19 Patients: A Report of Two Cases.

Hemophagocytic lymphohistiocytosis (HLH) is a disease that can affect both children and adults. HLH can be categorized as primary or secondary. Secondary HLH (sHLH) may be secondary to various viral infections.

Tumour Behaviour of Low-Grade Papillary Urothelial Carcinoma: A Single-Centre Retrospective Study.

Background and objective Carcinoma of the urinary bladder is the most common urological cancer, and it accounts for 3.9% of all cancer cases in men. Patients with the subset of noninvasive low-grade papillary urothelial carcinoma (LG-UrCa) are at higher risk for tumour recurrence.

Association of Co-dominant Immunoglobulin G Deposit in Immunoglobulin A Nephropathy With Poor Clinicopathological and Laboratory Parameters.

Introduction: Immunoglobulin A (IgA) nephropathy is the commonest primary glomerulonephritis with a wide range of clinical presentations and laboratory findings. There is a paucity of studies regarding the significance of co-dominant immunoglobulin G (IgG) deposition in IgA nephropathy.

Methods: The study included retrospective and prospective biopsy-proven cases of IgA nephropathy from 2013-2020 with a minimum of eight glomeruli.

De novo chronic lymphocytic leukemia/prolymphocytic leukemia or B-cell prolymphocytic leukemia? The importance of integrating clinico-morphological and immunophenotypic findings in distinguishing chronic lymphoproliferative diseases with circulating phase.

B-cell prolymphocytic leukemia (B-PLL) is an extremely rare disease, accounting for approximately 1% of the lymphocytic leukemias. B-PLL generally occurs in older people. It is characterized by the presence of more than 55% prolymphocytes in the peripheral blood (PB), no or minimal lymphadenopathy, massive splenomegaly, and very high white blood cell counts.

Analysis of aminoacids pattern in receptor tyrosine kinase using Boolean association rule.

Cancers are characterized by unrestricted cell division and independency of growth factor and other external signal responsiveness. Eukaryotic parental cells of tumors, on the other hand, constitute tissues and other higher structures like organs and systems and are capable of performing various functions in a highly co-ordinated fashion. Hence, cancer cells may be considered as entities capable of incessant growth and cell division but lacking any evolutionarily advanced intracellular or intercellular regulation.

Synthesis of superacid-functionalized mesoporous nanocages with tunable pore diameters and their application in the synthesis of coumarins.

Here we demonstrate for the first time the preparation of a triflic acid (TFA)-functionalized mesoporous nanocage with tunable pore diameters by the wet impregnation method. The obtained materials have been unambiguously characterized by XRD, N(2) adsorption, FTIR spectroscopy, and NH(3) temperature-programmed desorption (TPD). From the characterization results, it has been found that the TFA molecules are firmly anchored on the surface of the mesoporous supports without affecting their acidity.