Effect of dibenz(b,f)-1,4-oxazepine aerosol on the breathing pattern and respiratory variables by continuous recording and analysis in unanaesthetised mice.

A riot control agent has to be a sensory irritant of a reversible type without pulmonary irritation as the later can cause lung injury. The aim of the present study is to continuously record and analyse breathing pattern and respiratory variables of dibenz (b,f)-1,4-oxazepine (CR) in unanaesthetised mice during and after exposure. The lowest concentration of 0.

A derivatization strategy for the detection and identification of volatile trialkylphosphites using liquid chromatography-online solid phase extraction and offline nuclear magnetic resonance spectroscopy.

We demonstrate herein the application of selective derivatization method that converts volatile and labile trialkylphosphites (TAPs) into virtually non-volatile, thermally stable, and UV absorbing derivatives. After simple sample preparation, purification/enrichment of the derivatives was achieved by using high performance liquid chromatography (HPLC) coupled to on-line post column solid phase extraction (SPE) system. These derivatives were subjected to (31)P{(1)H} NMR and 1D-selTOCSY experiments.