Publications by authors named "Pranab S Basu"
Background: Antibodies against cyclic citrullinated peptide (anti-CCP) were thought to be more specific than rheumatoid factor (RF) for the diagnosis of rheumatoid arthritis (RA). The determination of anti-CCP in addition to RF could be helpful in the serological diagnosis and monitoring of patients with RA. Citrullination of proteins involves the enzymatic conversion of protein containing arginine residues to citrulline residues by the enzyme peptidylarginine deiminase (PAD).
View Article and Find Full Text PDFThis study was undertaken to distinguish between normal and diabetic subjects by lectin-glycated hemoglobin interaction. The quantitative precipitin method was performed for the interaction between glucose-specific lectin Concanavalin A (Con A) and the glucose-containing RBC-lysate for the estimation of calculated HbA1c% from a standard curve. The standard curve was prepared by plotting the optical density of the precipitin for the interaction of standard HbA1c concentration with Con A against HbA1c reference standard.
View Article and Find Full Text PDFObjectives: The present investigation was designed to distinguish prostate cancer and benign prostate hyperplasia by lectin-prostate specific antigen (PSA) binding.
Design And Methods: The quantitative precipitin method of concanavalin A (Con A)-carbohydrate interaction was explored with the serum PSA of patients suffering from prostatic complications.
Results: The carbohydrate content in the precipitate after binding of Con A with serum PSA of prostate cancer was significantly lower than that of benign prostate hyperplasia.
Background: A sugar-binding protein, lectin, was identified in the cystic fluid of brain tumor (glioma).
Methods: The protein was purified by high performance liquid chromatography.
Results: The molecular weight of the lectin was 29 kDa.