Tumor infiltrating lymphocytes profile and response in neoadjuvant chemotherapy-treated triple-negative breast carcinoma patients.

Background: Triple negative breast carcinoma (TNBC) has the highest mortality among all the breast carcinoma subtypes, but paradoxically, it shows the best response to neoadjuvant chemotherapy (NACT). Tumor infiltrating lymphocytes (TIL) density has been shown to have prognostic significance in TNBC. However, there are limited data on TIL subpopulation and their association with response to NACT in TNBC.

Comparative Study of Imprint Cytology and Histopathology of Soft Tissue Tumors.

Background: The components of soft tissue are fibroblasts, collagen, vascular structures, fatty tissue, skeletal muscles, smooth muscles, and neural tissue. The real incidence of soft tissue tumors (STTs) is difficult to estimate because most of them are benign (Benign: Malignant-100:1).

Aims: The aim of the present study was undertaken to note the patterns of presentation of patients with STTs and to evaluate the findings of imprint cytology (IC) and histopathological examination (HPE) of STTs.

A clinicopathological study of mediastinal masses operated in a tertiary care hospital in Eastern India in 3 years with special reference to thymoma.

Introduction: The mediastinum is the central portion of the thoracic cavity, limited by pleural cavities laterally, thoracic inlet superiorly, and the diaphragm inferiorly. Housing numerous organs, it is a veritable Pandora's box, within which various lesions may develop. This study was conducted to assess the epidemiologic profile, clinicoradiological features, cytological, and histopathological findings in patients presenting with mediastinal masses in a tertiary care hospital over a period of 3 years.

Carcinosarcoma of ovary with its various immunohistochemical expression: Report of a rare case.

Ovarian carcinosarcoma is an extremely rare tumor with an incidence of <2%. A report of such a rare case in a 40-year-old multiparous woman is being presented here. The patient complained of abdominal pain and distension.

Clear cell sarcoma of the kidney: a case report.

Clear cell sarcoma of the kidney is a rare malignant neoplasm of childhood, known for its aggressiveness, its tendency for recurrence, and to metastasize to bone. We report the observation of 8-month-old child presenting with a large abdominal mass. Clinically, it was diagnosed as Wilm's tumor, and left nephrectomy was done.

Malignant lymphoma in Eastern India: a retrospective analysis of 455 cases according to World Health Organisation classification.

Background: Malignant lymphoma (ML) is one of the most common cancers and is most prevalent in developed countries. The distribution of different subtypes of ML varies in the different geographical locations according to World Health Organization (WHO) classification.

Aims And Objectives: The study was aimed to analyze different patterns of ML in Eastern India and to compare it with other geographical locations.

Tumours of minor salivary glands--a clinicopathologic study.

The salivary gland system comprises 3 pairs of major glands ie, parotid, submandibular and sublingual and also thousands of lobules of minor salivary glands dispersed in oral cavity, nasal cavity, maxillary sinuses and upper airways. Most of the studies on salivary gland tumours included both major and minor salivary glands. Objectives of this study were to see the age, sex and site distribution of minor salivary gland tumours as well as cytohistologic correlation during their diagnosis.

Primary cutaneous large B-cell lymphoma, leg type: Report of two cases and review of literature.

Primary cutaneous large B-cell lymphoma, leg type (PCLBCL-LT), is very rare neoplasm presenting on and confined to leg(s). PCLBCL-LT is distinguished from other type of primary cutaneous B-cell lymphoma (PCBCL) by its frequent relapses and poorer prognosis. We report, two cases of PCLBCL-LT, occurring in two younger patients compared to published cases in literature.

High-grade plasmablastic neoplasm of humerus in an HIV-negative patient, which was indeterminate between plasmablastic lymphoma and plasmablastic myeloma.

Plasmablastic lymphoma (PBL) of bone is a rare neoplasm that shares many confusing cytomorphological and immunohistochemical features with plasmablastic plasma cell myeloma (PBPCM). A 47-year-old female patient presented with a bony swelling and bone pain in the left humerus for the last 6 months. On radiological examination (x-ray and computed tomography) it appeared to be a lytic lesion, and a pathological fracture was detected.

Comparison of vaginal misoprostol tablets and prostaglandin E2 gel for the induction of labor in premature rupture of membranes at term: a randomized comparative trial.

Aim:  To compare immediate induction with vaginal misoprostol tablets and immediate induction with vaginal dinoprostone (naturally occurring prostaglandin E2 [PGE2]) gel in women with premature rupture of membranes (PROM) at term.

Methods: Two hundred and twelve women with PROM at term were assigned randomly to receive either an intravaginal 25 µg misoprostol tablet, 4-hourly, with a maximum of five doses, or 0.5 mg intravaginal PGE2 gel, 6-hourly, with a maximum of two doses.

Adrenal myelolipoma with abdominal pain: A rare presentation.

Adrenal myelolipomas are rare benign tumors. Most of the cases are asymptomatic and discovered incidentally. We are reporting a case of myelolipoma involving right adrenal cortex of a 40-year-old woman who presented with abdominal pain.

Comparison of intramuscular magnesium sulfate with low dose intravenous magnesium sulfate regimen for treatment of eclampsia.

Objectives: Our objective was to compare intramuscular (i.m.) magnesium sulfate with a low dose intravenous (i.

Mature teratoma of the mesentery.

Teratoma of the mesentery is an extremely rare tumour of the germ cells and imposes diagnostic dilemma in clinical practice and is reported because of its very uncommon occurrence. With the advent of modern imaging modalities like ultrasonography, computerised tomography (CT) and magnetic resonance imaging (MRI), it is now confidently diagnosed and rarely requires diagnostic laparotomy. CT shows characteristic appearance (Rokitansky sign).