Publications by authors named "Pramod K Ponna"

Article Synopsis
  • Takotsubo cardiomyopathy (TTC) primarily affects postmenopausal females, but recent data show that men have worse outcomes, especially with cardiogenic shock (TTC-CS).
  • In a study analyzing hospitalizations for TTC-CS, 74.1% of cases were female, yet male patients had higher mortality rates and complications such as cardiac arrest and acute kidney injury.
  • Despite males experiencing higher hospitalization costs and longer stays, there were no significant differences in readmission rates over 30, 90, and 180 days, suggesting stable mortality with declining use of certain treatments.
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Background: Chronic kidney disease (CKD) and end stage renal disease (ESRD) are associated with increased risk of bleeding events, including hemorrhagic stroke, and periprocedural and gastrointestinal bleeding among patients with atrial fibrillation who are on anticoagulation. Safety of percutaneous left atrial appendage occlusion (LAAO) among this patient population has been uncertain with studies showing contradictory results.

Methods: PubMed and Google Scholar databases were queried for studies comparing outcomes among patients with and without significant CKD, and with and without ESRD who underwent LAAO device implantation.

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Article Synopsis
  • Transcatheter aortic valve replacement (TAVR) is becoming more common in the U.S., especially among patients with severe aortic stenosis, but there is limited research on its effectiveness for solid organ transplant (SOT) recipients and patients with liver cirrhosis.
  • A study using data from 2016 to 2020 compared outcomes between TAVR and surgical aortic valve replacement (SAVR) in these populations and found that TAVR is linked to significantly lower rates of in-hospital mortality and other adverse events compared to SAVR.
  • Both groups showed similar readmission rates after six months, but TAVR resulted in shorter hospital stays and lower costs compared to SAVR, highlighting
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A 73-year-old man with history significant for paroxysmal atrial fibrillation on apixaban underwent percutaneous coronary intervention (PCI) of the left anterior descending artery via transradial access. The patient was discharged on clopidogrel, atorvastatin, carvedilol, isosorbide mononitrate, losartan, and apixaban.

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We report a case of recurrent ST-segment elevation myocardial infarction (STEMI) due to a previously implanted under-expanded stent with in-stent thrombosis refractory to traditional interventional techniques. We underscore the utility of bail-out shockwave intravascular lithotripsy to tackle previously under-expanded stents in this acute setting.

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The transfemoral approach for transcatheter aortic valve replacement (TAVR) is superior to alternative access strategies. Only transfemoral access has been shown to have better clinical outcomes than surgical aortic valve replacement. In our patient, severe calcification of the distal abdominal aorta posed difficulty in using transfemoral access for TAVR.

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Post-flu-vaccination optic neuritis is an extremely rare condition with an incidence ranging from 0.003 cases to 0.89 per 100 000 population.

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The prevalence of tricuspid regurgitation (TR) increases with age, affecting 65%-85% of adults. Primary TR is caused by a congenital or acquired abnormality of the tricuspid valve apparatus (leaflets, chordae, papillary muscles, or annulus). Secondary TR is due to insufficient coaptation from dilation of tricuspid valve annulus due to the right ventricle (RV) or right atrium (RA) remodeling and increased RV pressures.

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We report a case of coronary artery fistula arising from the left main coronary artery in a 62-year-old patient presenting with atrial fibrillation. He underwent a transthoracic echocardiogram which suggested a possible coronary artery fistula. Cardiac computed tomographic angiography and cardiac catheterization confirmed the diagnosis.

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Lemierre's syndrome is a rare disease that generally occurs in young, healthy individuals, where an index of suspicion for something so serious is often low. There is no standardized definition of Lemierre's syndrome, which has led to a dilemma if Lemierre's can be diagnosed without internal jugular vein (IJV) thrombophlebitis. We highlight a complex case of Lemierre's syndrome that deviates from the classical presentation of the disease.

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