Publications by authors named "Prakasham Rumajogee"
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Synopsis of recent research by authors named "Prakasham Rumajogee"
- Prakasham Rumajogee's research focuses on understanding and addressing the mechanisms behind cerebral palsy (CP) and hypoxic-ischemic brain injuries, utilizing animal models to explore both therapeutic interventions and pathological processes.
- Key findings include the therapeutic potential of neural precursor cell (NPC) transplantation combined with constraint-induced movement therapy (CIMT) in promoting recovery in a hypoxic-ischemic mouse model, as well as the role of inflammation in worsening perinatal stroke outcomes, which can be mitigated by methylprednisolone administration.
- His studies highlight the significance of oligodendrocyte maturation and their impairment in CP while advocating for innovative regenerative strategies, including cell replacement therapies and understanding the inflammatory responses related to brain injury.
