Publications by authors named "Prakash Santhiyagu"

In the face of escalating environmental concerns, particularly the pervasive issue of non-biodegradable fast-food packaging waste, this study introduces a ground-breaking solution that not only addresses waste management but also advances biomedical technology. Utilizing the underexploited resource of Fucoidan, a sulfated polysaccharide from brown algae, we have innovatively transformed fast-food packaging waste into eco-friendly fluorescent carbon dots (FPCDs). These FPCDs were meticulously characterized through advanced techniques like FT-IR, TEM, and XRD, shedding light on their unique structure, morphology, and composition.

View Article and Find Full Text PDF

COVID-19 is a deadly pandemic caused by Corona virus leading to millions of deaths worldwide. Till today no medicine was available to cure this disease. This study selected 262 potential bioactive natural products derived from mangroves to inhibit the main protease (Mpro) and receptor-binding domain (RBD) protein of the COVID-19 virus.

View Article and Find Full Text PDF

Luminescent carbon dots have gained significant attention in various fields due to their unique optical properties and potential applications. Here, the study was aimed to propose a novel and sustainable approach for the synthesis of luminescent carbon dots (ICDs) using IV (Intravenous) medical bag waste. The ICDs were synthesized through a facile and cost-effective method that involved the carbonization of IV bag waste followed by surface functionalization with chitosan.

View Article and Find Full Text PDF

Actinobacteria are gram-positive bacteria with high G:C ratio in their genetic makeup. They have been noted and studied for their capacity to produce bioactive substances with a range of uses in human health, and they also exhibit a unique property of adapting to extreme environments quite well. Actinobacteria may play an essential role in cancer prevention and treatment due to their synthesis of anticancer compounds, as indicated by recent studies.

View Article and Find Full Text PDF

The present study explores the antifouling potentials of ethanol extract of mangrove . Results of antibacterial activity inferred that extract had strongly inhibited the growth of fouling bacterial strains with significant differences in halos (9-16 mm) and showed minimal bacteriostatic (12.5-100 µg ml) and bactericidal (25-200µg ml) values.

View Article and Find Full Text PDF

is an important etiological agent of catheter-associated urinary tract infections (CAUTIs) owing to its efficient crystalline biofilm formation and virulence enzyme production. Hence, the present study explicated the antibiofilm and antivirulence efficacies of 2-hydroxy-4-methoxybenzaldehyde (HMB) against in a non-bactericidal manner. HMB showed concentration-dependent biofilm inhibition, which was also evinced in light, confocal, and scanning electron microscopic (SEM) analyses.

View Article and Find Full Text PDF

The present study probed the antimicrobial potential of a rare mangrove associated actinomycetes against an array of aquatic bacterial pathogens causing disease outbreak in fin and shellfish. Antibacterial activity results implied that the mangrove associated actinomycetes RAS7 exhibited striking inhibitory activity against the tested aquatic bacterial pathogens. Identification of strain RAS7 through polyphasic and 16S rRNA sequencing affirmed that the strain belongs to Rhodococcus sp.

View Article and Find Full Text PDF

This study was aimed to investigate the antifouling (AF) potentials and toxic properties of methanol extract from leaves of mangrove Excoecaria agallocha. Antimicrofouling activity results inferred that this extract strongly inhibited fouling bacterial and microalgal growth. This extract had also inhibited the settlement of brown mussel Perna indica and larvae of barnacle Balanus amphitrite.

View Article and Find Full Text PDF

Marine bionanotechnology is one of the most promising areas of research in modern science and technology. Although there are multitude methods for the synthesis of nanoparticles (NPs), there is an increasing attention in developing high-yield, low-cost, non-toxic and eco-friendly procedures. The vital advantages of greener synthesis are cost-effective, reduced usage of toxic chemicals and abundant availability of resources.

View Article and Find Full Text PDF

In the present study, evaluation of antimicrobial, antioxidant, phytochemical constituents and toxicological properties of six coastal medicinal plants (CMP's) such as Ipomea biloba, Cantharanthus roseus, Cymbopogon citratus, Vitex negundo, Thespesia populnea and Pandanus tectorius was done. The maximum antimicrobial activity was recorded by methanolic extracts of V. negundo and T.

View Article and Find Full Text PDF

Silver and gold nanoparticles were synthesized using an aqueous extract of the seaweed Turbinaria conoides and their antibiofilm activity against marine biofilm forming bacteria is reported here. The UV-Vis spectra showed the characteristics SPR absorption band for Ag NPs at 421 and for Au NPs at 538 nm. Further, the synthesized nanoparticles were characterized using FT-IR, XRD, FESEM, EDX, and HRTEM analysis.

View Article and Find Full Text PDF

The present study documents the antifouling and toxic properties of seagrasses Syringodium isoetifolium and Cymodocea serrulata. For that, the seagrasses S. isoetifolium and C.

View Article and Find Full Text PDF

A probiotic bacterium isolated from the gut of wild shrimp Penaeus monodon rendered maximum antagonistic activity against shrimp pathogens and was capable of producing extracellular enzymes. The probiotic bacterium was identified as Bacillus cereus through 16S rRNA sequencing. The lyophilized B.

View Article and Find Full Text PDF

Background: Aquaculture is one amongst the growing and major food producing sectors. Shrimp culture is one of the subsectors of aquaculture that attracts more attention because of the economic interest. However, the shrimp culture systems have been facing severe consequences and economical losses due to disease outbreaks.

View Article and Find Full Text PDF