Health-related quality of life among lower limb amputees using prostheses in Nepal: a cross-sectional study.

Introduction: Lower limb amputation significantly impacts individuals' quality of life, with prostheses playing a crucial role in rehabilitation and mobility restoration. In Nepal, where access to advanced medical care is limited, understanding the factors affecting the well-being of prosthesis users is essential for optimizing rehabilitation services. This study investigates the sociodemographic and health-related variables influencing the quality of life among lower-limb amputees using prostheses in Nepal.

Modulation of Lung Function by Increased Nitric Oxide Production.

Introduction: Cigarette smoking reduces endogenous Nitric Oxide (NO) production by reducing Nitric Oxide Synthase (NOS) activity, which is one of the probable reason for increased rate of pulmonary diseases in smokers. Nitric oxide/oxygen blends are used in critical care to promote capillary and pulmonary dilation to treat several pulmonary vascular diseases. Among several supplements, the highest NOS activation has been proved for garlic with its unique mechanism of action.

Nerve Conduction Study on Sural Nerve among Nepalese Tailors Using Mechanical Sewing Machine.

Introduction: The use of new technologies and innovations are out of access for people living in a developing country like Nepal. The mechanical sewing machine is still in existence at a large scale and dominant all over the country. Tailoring is one of the major occupations adopted by skilled people with lower socioeconomic status and education level.

Vibration upshot of operating mechanical sewing machine: an insight into common peroneal nerve conduction study.

Background: Most of the people associated with tailoring occupation in Nepal are still using mechanical sewing machine as an alternative of new technology for tailoring. Common peroneal nerves of both right and left legs are exposed to strenuous and chronic stress exerted by vibration and paddling of mechanical sewing machine.

Methods: The study included 30 healthy male tailors and 30 healthy male individuals.

Association between obesity and heart rate variability indices: an intuition toward cardiac autonomic alteration - a risk of CVD.

Background: Obese people have a higher prevalence of cardiovascular disease, which is supposed to be due to autonomic dysfunction and/or metabolic disorder. The alterations in cardiac autonomic functions bring out the changes in the heart rate variability (HRV) indicators, an assessing tool for cardiac autonomic conditions.

Objective: To compare the cardiac autonomic activity between obese and normal weight adults and find out the highest association between the indices of HRV and obesity.

Somatic neural alterations in non-diabetic obesity: a cross-sectional study.

Background: Reports on alterations in somatic neural functions due to non-diabetic obesity, a major risk factor for diabetes, are few and still a matter of debate. Nevertheless, to our knowledge, reports lack any comments on the type of somatic nerve fibers affected in non-diabetic obesity. Therefore, this study aimed to find out the alteration in somatic neural functions in non-diabetic obese persons if any.

Nerve conduction studies in lower limb of elite Nepalese football players: an insight into neural adaptations.

Background: The study was aimed to assess somatic neural alterations in lower limbs of elite Nepalese football players by comparing their nerve conduction parameters with non-athletic controls.

Methods: Players (N.=27, age 22.