Publications by authors named "Prakash Gurung"

Article Synopsis
  • Neuro-ophthalmic issues, which can lead to permanent visual problems, are common in patients with traumatic head injuries but often overlooked, prompting the study to investigate their occurrence, neurological status, and neuroimaging results.
  • A total of 377 patients with head injuries were examined; most were males (71.9%), with road traffic accidents being the leading cause; 10.1% showed neuro-ophthalmic manifestations, primarily optic neuropathy.
  • Significant associations were found between brain contusions and optic neuropathy, as well as skull fractures and trochlear nerve palsy, highlighting the importance of early neuro-ophthalmic assessments in head injury patients.*
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Background: The conventional one-size-fits-all approach has been criticized for almost all drugs used especially for chronic diseases, including gout. The present study was aimed to explore the need of individualization and optimization of the dose of anti-gout medications among gout patients.

Methods: Cross-sectional study was carried out among 384 randomly selected new gout patients visiting two gout treatment centers at Lalitpur Metropolitan City, Nepal and who were taking antigout medications.

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Background: Aldosterone antagonists (AA) improve survival in ST elevation myocardial infarction (STEMI) patients with left ventricular ejection fraction(LVEF) "T40% ,with either clinical heart failure or diabetes mellitus. Our aim was to assess the adherence of AA use in Shahid Gangalal National Heart Centre, Kathmandu, Nepal.

Methods: Medical records of 171 STEMI patients with LVEF "T40% and discharged from our centre between January 2012 and December 2012 were retrospectively reviewed, regarding the use of AA use.

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Introduction: Percutaneous transvenous Mitral Commissurotomy (PTMC) has been shown to be a valid alternative to surgical therapy in selected patients with mitral stenosis. Though its efficacy in children and young adults is already established, its role in elderly patients is not well reported. We aimed to evaluate the efficacy of PTMC in elderly patients (≥60 years).

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Cabbage (Brassica rapa var. pekinensis) and Wisconsin Fast Plants (Brassica rapa) were chosen for a proof of concept study to determine the potential uptake and accumulation of human pharmaceuticals by plants. These plants were grown hydroponically under high-pressure sodium lamps in one of two groups including a control and test group exposed to pharmaceuticals.

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