Pharmaceutical standardization of Mamajjaka (Enicostemma littorale Auct. non Bl) Ghana.

Mamajjaka (Enicostemma littorale Auct. non Bl) is a well known folklore medicine frequently used for the treatment of Madhumeha (diabetes mellitus). There is no direct reference available for its antihyperglycaemic activity in Ayurvedic classics.

Clinical efficacy of two different samples of Shirishavaleha in Tamaka Shwasa (Bronchial Asthma).

Incidences of Bronchial Asthma have been raised in recent decades due to increased industrialization and pollution. This miserable condition can be compared with Tamaka Shwasa in Ayurveda. Modern synthetic drugs will provide instant relief in these cases, but are tend to develop a number of adverse drug reactions.

Nucleo-cytoplasmic trafficking of TRIM8, a novel oncogene, is involved in positive regulation of TNF induced NF-κB pathway.

TNF induced nuclear factor kappa B (NF-κB) is one of the central signaling pathways that plays a critical role in carcinogenesis and inflammatory diseases. Post-translational modification through ubiquitin plays important role in the regulation of this pathway. In the current study, we investigated the role of TRIM8, member of RING family ubiquitin ligase in regulation of NF-κB pathway.

Formulation and evaluation of floating matrix tablet of stavudine.

Background/aim: The purpose of the study was to prolong the gastric residence time of stavudine by designing its floating tablets and to study the influence of different polymers on its release rate.

Materials And Methods: The floating mix matrix tablets of stavudine were prepared by melt granulation method. Beeswax was used as hydrophobic meltable material.

Systematic analysis of small RNAs associated with human mitochondria by deep sequencing: detailed analysis of mitochondrial associated miRNA.

Mitochondria are one of the central regulators of many cellular processes beyond its well established role in energy metabolism. The inter-organellar crosstalk is critical for the optimal function of mitochondria. Many nuclear encoded proteins and RNA are imported to mitochondria.

Azeotropic mixture used for development and validation of Lornoxicam in bulk and its tablet dosage form by spectrophotometric method.

A novel, safe, economic and sensitive method of spectrophotometric estimation has been developed using Azeoptropic mixture (water:methanol: 60:40, v/v) for the quantitative determination of Lornoxicam, a practically water-insoluble drug. Hence, Lornoxicam stock solution was prepared in Azeoptropic mixture. Lornoxicam showed maximum absorbance at 383 nm.

Coronomaxillary space and its significance in complete denture retention--case reports.

The coronomaxillary space defines the distal-most extension of the maxillary denture border, and it usually is tightened during mouth opening. It has been reported that its adequate filling or overfilling is helpful in prosthesis retention. Two types of individual anatomical variations can affect the size of this space: vertical or lateral.

Effect of shodhana treatment on chronic toxicity and recovery of aconite.

Aconite is one of the poisonous plants used therapeutically in practice of Ayurveda after proper treatment called as 'Shodhana'. To determine the effect of Shodhana treatment on chronic toxicity and to assess the effect of recovery period after chronic toxicity of aconite. Raw aconite (RV), urine treated aconite (SM), and milk treated aconite (SD) were administered in 6.

Standardization of Shirishavaleha with reference to physico-chemical characteristics.

Ten batches of Shirishavaleha were prepared by using Twak (Bark) and Sara (Heartwood) of Shirisha [Albizzia lebbeck Benth]. The adopted formulation was based on Shirisharishta of Bhaishajya Ratnavali. Though Shirisharishta has significant therapeutic effect in cases of Tamaka swasa, etc.

Critical review on the pharmaceutical vistas of Lauha Kalpas (Iron formulations).

Iron is one among the major metals present in the earth's crust and is essential for sound sustenance of human body. Its deficiency leads to various health ailments. Contemporary medicine advises iron supplements in iron deficiency anemia.

Effect of different Avaleha in the management of Tamaka Shwasa (Bronchial Asthma).

Avaleha, which are generally elegant preparations, can be used for both preventive and curative purposes. Many research works have been carried out on different Avalehas. A number of studies with different Avalehas and their respective clinical efficacy in Tamaka Shwasa (Bronchial Asthma) have been carried-out at Department of Rasashastra and Bhaishajya Kalpana, IPGT & RA, Jamnagar.

Preparation of dhatryarishta by dhatri swarasa and dhatri kwatha.

Dhatryarishta has been described for the first time in Charaka Samhita, in the context of Panduroga. The same reference is available in Chakradatta, Bhaishajya Ratnavali, and Sahastrayogam too. Generally Dhatri Swarasa [Amalaki (Emblica officinalis Gaertn.

Evaluation of immunomodulatory activity of "Shirishavaleha"-An Ayurvedic compound formulation in albino rats.

The immunomodulatory activity of Shirishavaleha prepared from two different parts of Shirisha (Albizia lebbeck Benth), i.e., Twak (Bark) and Sara (Heartwood) as main ingredients was evaluated for humoral antibody formation and cell-mediated immunity in established experimental models.

A comparative evaluation of effect of upper lip length, age and sex on amount of exposure of maxillary anterior teeth.

Aim: The aim was to evaluate the relationship of age, sex and lip length to the amount of exposure of maxillary incisors and canine teeth.

Materials And Methods: Two-hundred subjects were enrolled in the study. All subjects were grouped according to the lip length and age.

Effect of cranial osteopathic manipulative medicine on cerebral tissue oxygenation.

Context: The use of cranial osteopathic manipulative medicine (OMM) to alter cerebral tissue oxygen saturation could play a role in the maintenance of cerebral homeostasis.

Objective: To examine the effects of cranial OMM on cerebral tissue oxygen saturation (S(CT)O(2)) and cardiac autonomic function in healthy adults.

Methods: Cranial OMM augmentation and suppression techniques and sham therapy were randomly applied to healthy adults.

Standard manufacturing process of Makaradhwaja prepared by Swarna Patra - Varkha and Bhasma.

Makaradhwaja is an important Kupipakwa Rasayana. It is prepared by using Swarna (gold), Parada (mercury) and Gandhaka (sulfur) in different ratios, i.e.

A clinical review of different formulations of Vasa (Adhatoda vasica) on Tamaka Shwasa (asthma).

Vasa (Adhatoda vasica Linn.) is a well known and easily available drug in almost all the seasons. Easy availability of any drug gains popularity among physicians as well as pharmaceuticals and this is the reason why almost every Kalpana of Vasa is found described in the Ayurvedika text.

Standardization of Gaja Puta and Ardha Gaja Puta in the preparation of Vanga Bhasma.

The Vanga Bhasma is an important one amongst the metallic Bhasmas. Mainly Gaja Puta, Ardhagaja Puta and Laghu Puta have been described for Marana of Vanga. The medicines, which are prepared from Gaja Puta, are said to be the best ones (Mahagunavidhayaka).

A comparative pharmacological evaluation of Taila (oil) and Ghrita (ghee) prepared with Guduchi (Tinospora cordifolia).

Guduchi (Tinospora cordifolia wild miers) is a well-known medicinal plant, which is abundantly used in different ayurvedic formulations utilizing varieties of media. The drug has properties like Rasayana (rejuvenating property), Krimighna (anthelmintics), and Kushtghna (used in skin disorders), as described in ayurvedic literature. Taila (oil) and Ghrita (ghee) are used as media in Ayurvedic Sneha (oleaginous) formulations.

Therapeutic potentials of metals in ancient India: A review through Charaka Samhita.

The Ayurvedic system of medicine has stood the test of time for four millennia or more. The ancient seers found that drugs of different origin (herbal, metal or animal) in addition to codes of conduct and dietary regulations are suitable tools to maintain health in healthy and eradicating diseases in diseased. Use of metallic preparations in healthcare is a unique feature in this system.

Pharmacognostical and physicochemical evaluation of Agasti leaf.

Sesbania grandiflora (L.) Pers., commonly known as Agasti, is widely used in Ayurveda for the treatment of diseases and for processing of various formulations in Rasashastra.

Anti-inflammatory activity of Shirishavaleha: An Ayurvedic compound formulation.

The purpose of the present study was to evaluate the anti-inflammatory activity of Shirishavaleha prepared from two different parts of Shirisha (Albizia lebbeck Benth.), viz. the bark (Twak) and the heartwood (Sara).

Epidemic investigation of the jaundice outbreak in girdharnagar, ahmedabad, gujarat, India, 2008.

Background: Since 1976, seven outbreaks of hepatitis E occurred in Ahmedabad. Clusters of jaundice cases were reported on June 19, 2008, by a civic center, Girdharnagar ward, Ahmedabad.

Objectives: THE OBJECTIVES WERE AS FOLLOWS: (1) to identify the etiological agent, source of outbreak, and mode of transmission; (2) to propose a control measure based on the outbreak investigation.

Process standardization for rennet casein based Mozzarella cheese analogue.

A process for manufacture of Mozzarella cheese analogue (MCA) using rennet casein and plastic cream as protein and fat sources respectively was standardized. The formulation comprised of 25% plastic cream (72% fat), 27% rennet casein along with 3% tri-sodium citrate as emulsifying salt, 2% maltodextrin as binder, 0.55% lactic acid as pH regulator, 1% common salt for seasoning, 1% Mozzarella cheese bud as flavouring and 40.

Etiology based study of hypertension in an Ayurvedic approach.

Ayurveda symbolises holistic approach towards treating diseases and better prevention than cure as its one of the main motto.(1) In present paper, etiological based survey of 30 patients was carried out to assess dietary and habitual lifestyles of people suffering from hypertension, for this a detailed proforma based on classical etiological factors related to hypertension was used. After the detailed assessment it was found that, more percentage of etiological factors of Raktavaha Srotas (micro channels for the transportation of blood) (78.