The substantial rise in metabolic illnesses that has occurred in both developed and developing countries over the last three decades has been linked to an increase in sugar-added foods and sweetened beverage intake. The significance of advanced glycation end products (AGEs) in the pathophysiology of metabolic diseases related to modern nutrition is an emerging issue. Spices and herbs can potentially be potent AGE production inhibitors due to their high polyphenol content.
View Article and Find Full Text PDFInteractions of manganese dioxide nanoparticles (MnO NPs) with vital biomolecules namely deoxyribonucleic acid (DNA) and serum albumin (BSA) have been studied in association with different surfactants by using fluorescence (steady state, synchronous and 3D), UV-visible, resonance light scattering (RLS), dynamic light scattering (DLS), and sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). The esterase activity of serum albumin was tested in associations with MnO NPs and surfactants. The antioxidant potential of prepared NPs was also evaluated (DPPH method).
View Article and Find Full Text PDFGlycation and oxidative stress are the major contributing factors responsible for diabetes and its secondary complications. Aminoguanidine, a hydrazine derivative, is the only approved drug that reduces glycation with its known side effects. As a result, research into medicinal plants with antioxidant and antiglycation properties is beneficial in treating diabetes and its consequences.
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