Characteristics of patients hospitalised with traumatic brain injuries.

Aim: To investigate the volume, injury characteristics and journey of Te Manawa Taki/Midland (TMT) residents hospitalised with a traumatic brain injury (TBI).

Methods: A retrospective review of TMT Trauma Registry data between 1 January 2012 and 31 December 2019 was conducted. Eligible patients (n=4,875) were TMT residents hospitalised with an injury to the brain parenchyma.

Efficacy of herbomineral compounds and pathya (Ayurvedic dietary regime and physical exercise) in the management of Yakṛt Roga (Non-alcoholic fatty liver disease).

Background: Nonalcoholic fatty liver disease (NAFLD) also called as hepatic steatosis is a manifestation of excessive triglyceride accumulation in the liver. NAFLD has been described by histological features ranging from simple fatty liver, nonalcoholic steatohepatitis, progressive fibrosis, and liver failure.

Objective: The objective was to evaluate the effect of herbomineral drugs and pathya (Ayurvedic dietary regime and physical exercise) in the management of NAFLD.

Molecular genetic testing of beta-thalassemia patients of Indian origin and a novel 8-bp deletion mutation at codons 36/37/38/39.

Hemoglobinopathies are the most commonly inherited genetic disorders in India. Certain communities in India have a high predisposition to beta-thalassemia. To offer prenatal diagnosis and to prevent the birth of an affected child, mutation testing in clinically diagnosed beta-thalassemia patients/carriers is a prerequisite.

Rapid detection of alpha + thalassaemia deletion & alpha-globin gene triplication by Gap-PCR in Indian subjects.

Background & Objectives: Southern blot hybridization is the commonly used method to delineate alpha globin gene defects. This technique is time consuming, requires a large amount of genomic DNA and radioactive probes for detecting the mutations, which limits its use in diagnosis. The present paper emphasizes the efficacy of a well-established Gap-PCR technique in the Indian set up to detect defects of the alpha globin gene in clinics and laboratories engaged in the diagnosis of thalassaemias.