Methyl methacrylate-modified polystyrene microspheres: an effective strategy to enhance the fluorescence of Eu-complexes.

The detection applications of europium complex-doped microspheres mainly rely on strong fluorescence intensity and a well-defined morphology. In this work, using methyl methacrylate-modified polystyrene microspheres has been proven an effective strategy to enhance the fluorescence and morphology of Eu-complexes. The experimental results showed that the modification resulted in the formation of a porous structure within the polystyrene microspheres, enhancing the doping uniformity and facilitating a more significant accumulation of fluorescent molecules.

Temporally and spatially resolved molecular profiling in fingerprint analysis using indium vanadate nanosheets-assisted laser desorption ionization mass spectrometry.

This study presents the first-ever synthesis of samarium-doped indium vanadate nanosheets (IVONSs:Sm) via microemulsion-mediated solvothermal method. The nanosheets were subsequently utilized as a nano-matrix in laser desorption/ionization mass spectrometry (LDI-MS). It was discovered that the as-synthesized IVONSs:Sm possessed the following advantages: improved mass spectrometry signal, minimal matrix-related background, and exceptional stability in negative-ion mode.

Facile synthesis of noncytotoxic PEGylated dendrimer encapsulated silver sulfide quantum dots for NIR-II biological imaging.

Near-infrared-II (NIR-II, 1000-1700 nm) bioimaging features high penetration depth and high spatio-temporal resolution compared to traditional fluorescence imaging, but the key is to develop stable and biocompatible NIR-II fluorophores suitable for in vivo applications. Silver sulfide quantum dots (Ag2S QDs) have been demonstrated to be excellent for in vivo NIR-II imaging with unique optical properties and decent biocompatibility, but they often require complex post modifications for in vivo applications. Herein we demonstrate a facile one-pot strategy to synthesize PEGylated dendrimer-encapsulated Ag2S QDs useful for in vivo NIR-II imaging.

Reproducibility of "The Bethesda System for Reporting Thyroid Cytopathology:" A Retrospective Analysis of 107 Patients.

Objectives: Fine-needle aspiration cytology (FNAC) has emerged as an indispensable tool to discriminate thyroid lesions into benign or malignant for appropriate management. The need for simplicity of communication and standardization of terminology for thyroid FNAC reporting led to introduction of "The Bethesda system for reporting Thyroid Cytopathology" (TBSRTC) in a conference held at the National Cancer Institute in 2007. This study aims at establishing the reproducibility of TBSRTC for diagnosing thyroid lesions.