Publications by authors named "Prado Patricia"
Advancing Digital Education Technologies by Empowering Nurses With Point-of-Care Ultrasound: Protocol for a Mixed Methods Study.
Fernanda Raphael Escobar Gimenes Angelita Maria Stabile Rodrigo Magri Bernardes Vinicius Batista Santos Mayra Gonçalves Menegueti Patricia Rezende do Prado
JMIR Res Protoc
October 2024
Background: Bedside ultrasonography, also known as point-of-care ultrasound (PoCUS), is a promising technological tool that enhances clinical assessment, enriching diagnostic capabilities and clinical reasoning. Its use in nursing spans various patient populations and health care settings, providing nurses with a valuable health assessment tool to improve care quality and patient safety. Despite its growing integration into clinical practice, PoCUS training has mainly focused on physicians, leaving a gap for trained nurses who demonstrate similar proficiency in conducting scans and interpreting images.
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- - The Mediterranean mollusc has experienced population declines due to a significant mortality event linked to a parasite, but some localized populations have shown resilience possibly because of their specific environmental conditions.
- - Researchers developed a molecular multiplex PCR method to accurately identify species and detect hybrids, using species-specific primers targeting the Internal Transcribed Spacer (ITS) regions of selected bivalves.
- - The study analyzed samples from various Mediterranean areas, confirming species differentiation through DNA amplification and sequencing, thereby demonstrating the importance of molecular tools in conserving biodiversity and managing hybridization.
Polypharmacy and high-alert medications in patients with nasally placed feeding tube on admission and at hospital discharge: Multicenter cross-sectional study.
Fernanda Raphael Escobar Gimenes Juliana Santana de Freitas Janine Koepp Patrícia Rezende do Prado Rochele Mosmann Menezes
Explor Res Clin Soc Pharm
September 2024
Article Synopsis
- - A study examined the prescription patterns of medications for patients with nasally placed feeding tubes (NPFT) and found that 92% were on polypharmacy (multiple medications) upon admission, decreasing slightly to 84.7% at discharge.
- - High-alert medications (those that pose a significant risk if used inappropriately) made up over 17% of all prescriptions, with no significant change in their usage between admission and discharge.
- - The study highlights the need for coordinated care strategies to manage the medication risks associated with NPFT patients, particularly given their complex health conditions.
Article Synopsis
- * A study conducted on 27 P. nobilis individuals from both natural populations and captivity revealed differences in their immune competence, showing that hemolymph from captive animals had a significantly lower Total Hemocyte Count (THC) compared to those from the wild.
- * Flow cytometry and ultrastructure analysis indicated that captive pen shells exhibited impaired phagocytosis abilities against pathogens, likely caused by PnPV infection disrupting the hemocyte cyt
Article Synopsis
- There has been significant mass mortality of noble pen shell in various Mediterranean regions over the past seven years linked to a picornavirus that affects immune cells.
- A study analyzed specimens from Spain and Italy using electron microscopy and sequencing to identify the virus and understand its impact on the immune cells.
- Results showed the virus's presence in 100% of the samples, leading to lower total hemocyte counts and indicating severe immune dysfunction and viral replication in affected animals.
Article Synopsis
- Extreme storms like Storm Gloria can cause significant and lasting damage to seagrass ecosystems, particularly affecting foundational species like Posidonia oceanica.
- Following Storm Gloria in January 2020, surveys of seagrass meadows revealed that over half experienced shoot unburial, with some areas having up to 40 cm of sediment removed, while burial affected 10-80% of meadows.
- The research highlights that more exposed and patchy meadows are more susceptible to such extreme weather events, and it may take decades to centuries for these damaged seagrass ecosystems to recover, emphasizing the need for their protection against human impact.
Disease outbreaks in several ecologically or commercially important invertebrate marine species have been reported in recent years all over the world. Mass mortality events (MMEs) have affected the noble pen shell (), causing its near extinction. Our knowledge of the dynamics of diseases affecting this species is still unclear.
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- - The study focused on detecting a specific parasite that affects bivalves, utilizing water samples from diverse environments and analyzing infected bivalve mantle samples to characterize the parasite's ribosomal unit.
- - Researchers developed a method for environmental DNA (eDNA) detection by conducting PCR tests on water samples, assessing the level of DNA degradation and its implications for the parasite's infectious capacity.
- - The new detection method proved effective in identifying the parasite in sea waters with varying levels of DNA fragmentation, offering a valuable tool for monitoring and understanding the parasite's lifecycle and spread.
Nursing interventions to prevent corneal injury in critically ill sedated and mechanically ventilated patients: A systematic review of interventions.
Patrícia Rezende do Prado Renata Cristina Campos Pereira Silveira Mario Vianna Vettore Mariann Fossum Grete Lund Vabo
Intensive Crit Care Nurs
October 2023
Article Synopsis
- The study aimed to assess how effective different interventions are in preventing corneal injuries in critically ill patients who are sedated and on mechanical ventilation.
- A systematic review of 15 studies revealed that lubricants significantly reduced the risk of corneal injury compared to eye tape and ointments, with the lowest risk found in using polyethylene chambers.
- The findings suggest that ocular lubrication (preferably gel or ointment) and the use of polyethylene chambers are the best methods for protecting the eyes of these vulnerable patients in clinical settings.
Article Synopsis
- Amphipods are important small crustaceans found in seagrass meadows, yet their distribution patterns have not been well studied.
- This research examined twelve seagrass meadows (Cymodocea nodosa) across different biogeographical areas in the Mediterranean Sea and Atlantic Ocean, focusing on how various environmental factors affect amphipod populations.
- The study revealed that amphipod abundance and species richness are primarily influenced by habitat structure elements, such as seagrass leaf area and epiphyte biomass, indicating that more complex habitats support greater amphipod diversity.
Article Synopsis
- The protocol outlines a method to study SARS-CoV-2 infection by using human kidney organoids derived from pluripotent stem cells.
- It explains how to create a diabetic environment in these organoids to mimic real-life conditions.
- The document also includes instructions for preparing SARS-CoV-2 virus stocks and evaluating infection effects through immunofluorescence techniques.
Assessing kidney development and disease using kidney organoids and CRISPR engineering.
Front Cell Dev Biol
September 2022
Article Synopsis
- - The development of kidney organoids from human pluripotent stem cells (hPSCs) is a major breakthrough in regenerative medicine, offering a deeper understanding of kidney development and creating a basis for organ-like tissue systems.
- - Key insights into kidney morphogenesis and the influence of specific genes have been achieved through genome editing techniques, particularly CRISPR/Cas9, which facilitate the study of renal differentiation and related disease phenotypes.
- - Despite advancements such as single-cell RNA sequencing, kidney organoid technology faces limitations that could be addressed through bioengineering, improving the standardization and application of these models for research on kidney development and diseases.
Objective: To identify clinical indicators and nursing diagnoses with the highest risk of mortality in critically ill patients with COVID-19.
Method: Retrospective cohort with the population of adults and elderly people with COVID-19 from an Intensive Care Unit. Categorical variables were described using absolute and relative frequencies and risk factors for mortality using Cox regression, with a confidence interval of 95%.
Article Synopsis
- Key challenges included reorganizing service flow for COVID-19 cases, implementing structural changes in the hospital, and ensuring proper equipment and supply availability for quality patient care.
- The study emphasized the importance of staff training, managing stress and absenteeism, and maintaining the health of both patients and healthcare professionals for effective service resilience during the pandemic.
Article Synopsis
- Diabetic individuals may be more susceptible to severe COVID-19, but the reasons for this connection are not fully understood.
- Researchers created a human kidney organoid model to study how diabetic conditions affect SARS-CoV-2 infection, finding that diabetic-like organoids had higher viral loads than controls.
- The study also discovered that altering the metabolic processes in kidney cells from diabetic patients could reduce the susceptibility to the virus, suggesting potential new treatment approaches focusing on energy metabolism.
Article Synopsis
- The study aimed to determine how common adverse events are among critically ill patients in an intensive care unit and how much care they require.
- Conducted from January to March 2020, it analyzed incidents like pressure injuries, accidental extubation, and healthcare-associated infections, using a Nursing Activities Score to measure care hours provided.
- Results showed that over half of the 88 patients experienced adverse events, linked to increased care needs, severity of conditions, and longer hospital stays, indicating a critical shortage of nursing staff that could impact patient safety.
Article Synopsis
- The study compares light microscope (LM) identifications and DNA metabarcoding techniques to analyze benthic diatom communities in the Mediterranean Ebro delta bays, revealing a rich diversity of 249 taxa identified by LM.
- While DNA metabarcoding captures community diversity effectively at the genus level, it struggles at the species level due to incomplete DNA reference databases, but can identify rare and delicate diatom species not detected by LM.
- Combining both methods enhances ecological studies of benthic microalgal communities, providing a more comprehensive understanding than using either technique alone.
Article Synopsis
- - The study aims to validate the nursing diagnosis of "risk for corneal injury" in critically ill adults, emphasizing the need for ongoing research in diverse populations for clinical evidence.
- - Conducted in Northern Brazil, the prospective cohort study involved assessing 209 patients over 10 days, revealing that 76% were at risk, with 16.3% actually developing corneal injuries linked to identified risk factors.
- - Key risk factors include eyeball exposure, a Glasgow score under 6, and periorbital edema, which can inform nursing interventions and enhance the diagnosis's reliability within the NANDA International Taxonomy.
Article Synopsis
- The study aimed to outline essential nursing care procedures for administering bed baths to COVID-19 patients through a detailed literature review.
- The research involved five key stages, including framing the research question, searching relevant studies, assessing them, analyzing data, and presenting findings, ultimately narrowing down 55 publications to 15 relevant studies.
- The conclusion emphasizes the need for specific hygiene practices, appropriate personal protective equipment, and ongoing monitoring of vital signs to enhance patient safety during bed baths.
Article Synopsis
- - The study describes the experiences of a nurse caring for COVID-19 patients on hemodialysis who are positioned face down, revealing various challenges in resources and care delivery.
- - Conducted in a Brazilian philanthropic hospital from May to August 2020, the report underscores the importance of communication and implementing new care protocols to improve nursing practices during the pandemic.
- - The findings highlight the crucial role of nursing in patient care, promoting the need for further research to enhance nursing strategies and improve patient outcomes amid COVID-19 complications.
Article Synopsis
- The study aimed to identify risk factors for death in individuals severely affected by COVID-19, using data from a cohort of adults in Acre, Brazil, between March and September 2020.
- Analyzing over 57,700 individuals, the findings showed a significant incidence and mortality rate of COVID-19, with several key risk factors identified, including male gender, age over 60, dyspnea, and underlying health conditions like heart disease and diabetes.
- The conclusion emphasizes that male sex, older age, and specific health issues greatly increase the risk of death from COVID-19 in affected individuals.
Article Synopsis
- Loneliness and low social support can severely impact the health of individuals with Alzheimer's and their caregivers, a risk exacerbated by COVID-19 restrictions on gatherings.
- Memory Cafés are programs that allow those with dementia and their care partners to socialize in a judgment-free environment, and these have adapted to virtual formats during the pandemic.
- Semi-structured interviews revealed five key themes related to the benefits of Memory Cafés: reprieve, possibility, connectedness, inclusivity, and added value, highlighting their significance for families dealing with dementia.
Article Synopsis
- The pen shell, Pinna nobilis L., is facing critical endangerment due to a harmful parasite, which directly affects its population.
- This study uses stable isotopes, specifically δC and δN, to assess the nutritional status of both captive and wild pen shells, comparing their diets and nutrient assimilation.
- Results show that captive pen shells are experiencing significant nutritional stress, heavily relying on their own body reserves, while field specimens primarily obtain nutrition from zooplankton.
Article Synopsis
- The study aimed to analyze factors that influence the length of stay (LOS) and mortality rates in patients who were fed using nasogastric or nasoenteric tubes at multiple hospitals in Brazil.
- Data was collected from 365 patients between October 2017 and April 2019, focusing on various demographic and clinical factors to assess correlations with LOS and death.
- Key findings showed that older age, nursing care dependency, and complexity of care increased both LOS and risk of death, underlining the importance of identifying these factors for better nursing care planning.
Article Synopsis
- Herbivory plays a significant role in shaping seagrass communities, but knowledge on its biogeographical patterns and drivers is limited compared to those in terrestrial ecosystems.
- A study was conducted in Cymodocea nodosa meadows, spanning 2000 km and 13° latitude across two ocean basins, to explore factors affecting herbivory, including herbivore density, seagrass characteristics, and environmental conditions.
- Findings revealed that herbivory intensity is primarily influenced by fish density and seagrass size, with seasonal temperature variations being a key driver in temperate regions, while specific conditions in subtropical areas resulted in minimal herbivory.