Accuracy of Echocardiographic Cardiac Output Assessment by Critical Care Fellows.

Background: Advanced critical care echocardiography comprises a specific set of qualitative and quantitative point-of-care echocardiography skills, including a reliable, noninvasive method to measure cardiac output. This technique requires echocardiographic measurement of left ventricular outflow tract (LVOT) diameter and LVOT velocity time integral (VTI). Although there is a demand among critical care fellows to learn these advanced techniques, there are no data describing the acquisition of mastery in these skills.

Hepatoprotective efficacy of Argemone mexicana L. root in paracetamol-induced hepatotoxicity in a rat model.

Ethnopharmacological Relevance: Argemone mexicana L. (Papaveraceae), a weed that thrives in the tropical and subtropical areas of South and Central America, Mexico, Caribbean Islands and India. In India, it has been used traditionally to treat vesicular calculus, inflammatory conditions, and hepatobiliary disorders.

Comparative Evaluation of Crack Propagation During Root Canal Preparation in Primary Molar with Manual Instrumentation, ProTaper Universal and ProTaper Next Rotary File Systems: An Study.

Statement Of The Problem: Root canal preparation with rotary files causes dentinal cracks in root canals of primary teeth affecting their longevity.

Purpose: Nickel-titanium rotary files have been widely used for root canal preparation in primary teeth. The present study compared occurrence of dentinal microcracks in root canals of extracted primary molar teeth prepared using Hedstrom (H) files, ProTaper Universal rotary files, and ProTaper Next rotary file systems.

Profiling CARD14 gene expression in Indian Psoriasis patients.

Several Genome Wide linkage Studies on psoriasis performed to gain insight of genetic architecture of the disease. Caspase Recruitment Domain-containing family 14 (CARD14) also known as CARMA2 or BIMP2; cytogenic location: 17q25.3, is a scaffold protein that primarily controls the skin epidermis's nuclear factor kB (NF-kB) signaling pathway activity in skin epidermis, a master gene for inflammation, has been shown to be linked with rare, heritable form of psoriasis.

Therapeutic Potential of Neutralizing Monoclonal Antibodies (nMAbs) against SARS-CoV-2 Omicron Variant.

Background: The COVID-19 pandemic has spurred significant endeavors to devise treatments to combat SARS-CoV-2. A limited array of small-molecule antiviral drugs, specifically monoclonal antibodies and interferon therapy, have been sanctioned to treat COVID-19. These treatments typically necessitate administration within ten days of symptom onset.

Human Muscle Inspired Anisotropic and Dynamic Metal Ion-Coordinated Mechanically Robust, Stretchable and Swelling-Resistant Hydrogels for Underwater Motion Sensing and Flexible Supercapacitor Application.

Mechanically robust and anisotropic conductive hydrogels have emerged as crucial components in the field of flexible electronic devices, since they possess high mechanical properties and intelligent sensing capabilities. However, the hydrogels often swell on exposure to aqueous medium because of their hydrophilicity, which compromises their mechanical properties. Additionally, the hydrogels' isotropic polymeric networks demonstrate isotropic ion transport, which significantly diminishes the sensing capabilities of electrical devices based on hydrogels.

A doxorubicin loaded chitosan-poloxamer implant for the treatment of breast cancer.

Breast cancer is a serious concern for many women worldwide. Drug-loaded implants have shown several benefits over systemic administrations. To provide anti-cancer drugs with controlled release and reduced systemic toxicity, biodegradable implants have attracted a lot of attention.

Natural Teeth for Prosthetic Solutions in Pediatric Patients: Two Case Reports of Biologically Based Removable Functional Partial Dentures.

Prosthetic appliances are essential for promoting the proper development of teeth, dental arches, and facial bones in children. Due to the constantly changing nature of a child's oral environment, these appliances must be temporary and require regular maintenance and adjustment to avoid impeding orofacial growth. A fundamental aspect of contemporary dentistry is re-establishing aesthetics.

An Atypical Occurrence of Epidermoid Cyst in the Postauricular Parotid Region of a Young Child: A Case Report and Literature Review.

Benign epidermal cysts, also called epidermoid cysts, can sometimes develop in the orofacial region from trapped epidermal components without skin adnexal appendages. Congenital or acquired conditions could be the case. Epidermoid cysts have been found to occur in 6.

Quadriceps Muscle Layer Thickness and its association with frailty in critically ill patients: A prospective observational study.

Background: Frailty is a well-recognized clinical entity known to influence the outcomes of critically ill patients. Muscle ultrasound, particularly Quadriceps Muscle Layer Thickness (QMLT), assesses muscle mass, which is a key component determining frailty. However, no studies have assessed the association between frailty and QMLT.

Protective effect of Tecoma stans (L.) Juss.ex Kunth in CFA-induced arthritic rats.

Ethnopharmacological Relevance: Tecoma stans (L.) Juss.ex Kunth (Bignoniaceae) is mainly found in tropical and subtropical regions of Africa and Asia.

Insight into the removal of nanoplastics and microplastics by physical, chemical, and biological techniques.

Plastic pollutants create health crises like physical damage to tissues, upset reproductive processes, altered behaviour, oxidative stress, neurological disorders, DNA damage, gene expression, and disrupt physiological functions, as the biosphere accumulates them inadvertently through the food web. Water resources have become the generic host of plastic wastes irrespective of their particle size, resulting in widespread distribution in aquatic environments. The pre-treatment step of the traditional water treatment process can easily remove coarse-sized plastic wastes.

Cocaine- and Amphetamine-Regulated Transcript Peptide in the Central Nervous System of the Gecko, Hemidactylus leschenaultii: Molecular Characterization, Neuroanatomical Organization, and Regulation by Neuropeptide Y.

Neuropeptide cocaine- and amphetamine-regulated transcript (CART) is widely expressed in the brains of teleosts, amphibians, birds, and mammals and has emerged as a conserved regulator of energy balance across these vertebrate phyla. However, as yet, there is no information on CART in the reptilian brain. We characterized the cDNA encoding CART and mapped CART-containing elements in the brain of gecko, Hemidactylus leschenaultii (hl) using a specific anti-CART antiserum.

Comparative Evaluation of the Accuracy of Electronic Apex Locator and Digital Radiography for Working Length Determination in Primary Teeth: A Systematic Review.

Statement Of The Problem: It is challenging to perform a pulpectomy procedure in primary tooth because of its physiological root resorption and variation in root morphology. Working length measurement is considered to be one of the critical steps, as it determines the extent of obturation and apical seal.

Purpose: To compare the accuracy of electronic apex locator (EAL) and digital radiography (DR) for working length determination in primary teeth.

Choline chloride - oxalic acid dihydrate deep eutectic solvent pretreatment of Barley straw for production of cellulose nanofibers.

This study investigates the production of cellulose nanofibers (CNF) from Barley straw using ultrasound-assisted deep eutectic solvent (US-DES) treatment for biomass fractionation and subsequent high-intensity ultrasonication (HIUS) for nano-fibrillation. Two deep eutectic solvents (DES), synthesized from choline chloride (ChCl) and oxalic acid dihydrate (OAD) at 1:1 and 2:1 M ratio, achieved solubilisation of over 80 % of lignin and hemicellulose under optimal conditions. The purification of these DES-treated materials resulted in cellulose with a purity >88 %.

Exploring the Impact of Orthodontic Treatment on Temporomandibular Joint Health.

Background: Currently, one of the most prevalent oral abnormalities is malocclusion. There is a rising percentage of patients who are willing to undertake orthodontic procedures.

Aim: To evaluate the impact of orthodontic treatment on the morphology of temporomandibular joint (TMJ) in patients with malocclusion associated with TMJ abnormality such as skeletal class II deep bite malocclusion using CBCT.

Assessment of Chronic Malnutrition and Its Correlation With Oral Health Status in Children Aged Three to Six Years in Jabalpur District, India: An Epidemiological Study.

Objective: This study aims to examine the correlation of chronic malnutrition with the oral health status of children aged three to six years.

Methods: A total of 400 children were selected and divided into four groups based on z-scores. For evaluation of oral health status, teeth were examined for dental caries using the decayed, missing, and filled permanent teeth (DMFT) scores.

Nanoquercetin based nanoformulations for triple negative breast cancer therapy and its role in overcoming drug resistance.

Triple Negative Breast Cancer (TNBC) is a highly aggressive and treatment-resistant subtype of breast cancer, lacking the expression of estrogen, progesterone, and HER2 receptors. Conventional chemotherapy remains the primary treatment option, but its efficacy is often compromised by the development of drug resistance. Nanoquercetin has garnered the attention of researchers due to its potential in combating cancer.