Publications by authors named "Pradeep T Manchegowda"
Article Synopsis
- The study aimed to identify imaging features of vitreoretinal lymphoma (VRL) using various advanced imaging techniques linked to treatment with intravitreal Rituximab (IVR).
- Patients with primary VRL underwent a biopsy for diagnosis and were treated with monthly IVR injections until remission, with a total of 15 treatment-naive eyes included in the analysis.
- The outcomes included observed changes in imaging features such as decreased hyper-autofluorescence in active lesion areas, regression of retinal deposits, and various retinal complications, demonstrating the effectiveness of IVR treatment in managing VRL.
Purpose: To evaluate treatment outcomes and complications of intravitreal rituximab (IVR) monotherapy for eyes with vitreoretinal lymphoma (VRL).
Methods: Patients diagnosed with 'isolated primary VRL' or 'VRL with remission of systemic disease' and treated with IVR (1 mg/0.1 ml) between June 2014 and June 2019 were included in this retrospective, interventional case series.
Purpose: This work subclassifies retinoblastoma vitreous seeds and evaluates the efficacy, regression patterns, and adverse effects of combination intravitreal melphalan and topotecan chemotherapy for resistant and recurrent vitreous seeds.
Methods: A retrospective review of medical records was conducted of patients with retinoblastoma and resistant or recurrent vitreous seeds who were treated with intravitreal melphalan and topotecan injections from August 2014 to July 2018. Main outcome measures included regression pattern, time for regression, time for recurrence of seeds, treatment outcomes, and ocular toxicity.
Background: Mutations in gene has been reported to cause Retinitis pigmentosa (RP) and clinically appears discrete from other commonly encountered phenotypes. We report 14 patients who were seen to have CERKL mutation of the 152 patients of RP from Indian population who underwent genetic testing.
Materials And Methods: A retrospective analysis was performed in 28 eyes of the 14 unrelated patients to establish genotype phenotype correlation.
Retinopathy of prematurity (ROP) is a vasoproliferative disease of developing retinal vessels that affects premature infants and can lead to severe and irreversible visual loss if left untreated. India and some other Asian countries are in the middle of a 'third ROP epidemic'. Blindness due to ROP is largely preventable if appropriate, adequate and accessible screening programmes are available.
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