In vivo toxicological evaluation of 3-benzylideneindolin-2-one: antifungal activity against clinical isolates of dermatophytes.

Background: Dermatophytes, the primary causative agents of superficial cutaneous fungal infections in humans, present a significant therapeutic challenge owing to the increasing prevalence of recurrent infections and the emergence of antifungal resistance. To address this critical gap, this study was designed to investigate the antifungal potential of 3-benzylideneindolin-2-one against dermatophytes and assess its in vivo toxicological profile using brine shrimp and zebrafish embryo models.

Methods: The antifungal activity of 3-benzylideneindolin-2-one was evaluated against 30 clinical isolates of dermatophyte species, including Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum gypseum, Microsporum canis, and Epidermophyton floccosum, by determining the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) using the broth microdilution method.

Catalytic reduction of 4-nitrophenol using CuO@NaTi(PO)⋅HO.

This article presents the synthesis, property characterization and catalytic application of CuO-supported disodium titanium phosphate, (CuO@NaTi(PO)⋅HO) for the reduction of industrial pollutant 4-nitrophenol (4-NP). A simple hydrothermal route was developed to synthesize CuO@NaTi(PO)⋅HO catalyst (CuO@NaTiP) from beach sand ilmenite. The prepared CuO@NaTiP was characterized using X-ray diffraction, scanning electron microscopy, energy dispersive X-ray analysis, X-ray photoelectron spectroscopy, and nitrogen adsorption-desorption isotherms.

Facile Synthesis of Titanium Phosphates from Ilmenite Mineral Sand: Potential White Pigments for Cosmetic Applications.

Ilmenite mineral sand was used to synthesize titanium bismonohydrogen orthophosphate monohydrate, Ti(HPO)·HO, and titanium phosphate, TiPO, two white pigments suitable in cosmetic applications. Ti(HPO)·HO was obtained after digesting ilmenite in 85% phosphoric acid at 150 °C for 5 hours. On standing, unreacted ilmenite and white Ti(HPO)·HO solid separated into two layers and Ti(HPO)·HO was calcined at 900 °C to obtain the crystalline TiPO.

Biosynthesized silver nanoparticles: are they effective antimicrobials?

Background: Silver nanoparticles (AgNPs) are increasingly being used in medical applications. Therefore, cost effective and green methods for generating AgNPs are required.

Objectives: This study aimed towards the biosynthesis, characterisation, and determination of antimicrobial activity of AgNPs produced using Pseudomonas aeruginosa ATCC 27853.

Surface photochemistry of adsorbed nitrate: the role of adsorbed water in the formation of reduced nitrogen species on α-Fe2O3 particle surfaces.

The surface photochemistry of nitrate, formed from nitric acid adsorption, on hematite (α-Fe2O3) particle surfaces under different environmental conditions is investigated using X-ray photoelectron spectroscopy (XPS). Following exposure of α-Fe2O3 particle surfaces to gas-phase nitric acid, a peak in the N1s region is seen at 407.4 eV; this binding energy is indicative of adsorbed nitrate.

XPS study of nitrogen dioxide adsorption on metal oxide particle surfaces under different environmental conditions.

The adsorption of nitrogen dioxide on gamma aluminium oxide (gamma-Al(2)O(3)) and alpha iron oxide (alpha-Fe(2)O(3)) particle surfaces under various conditions of relative humidity, presence of molecular oxygen and UV light has been investigated. X-Ray photoelectron spectroscopy (XPS) is used to monitor the different surface species that form under these environmental conditions. Adsorption of NO(2) on aluminum oxide particle surfaces results primarily in the formation of surface nitrate, NO(3)(-) with an oxidation state of +5, as indicated by a peak with binding energy of 407.

Electronic and photophysical properties of a novel phenol bound dinuclear ruthenium complex: evidence for a luminescent mixed valence state.

A novel dinuclear ruthenium(II) complex bridged by dianionic bridge 3-(2-phenol)-5-(pyridin-2-yl)-1,2,4-triazole in which the ruthenium metal atoms are bound through N,N coordination to the pyridine and triazole and O,N coordination to the triazole and phenolate is described. The electrochemical, spectroscopic and photophysical behaviour of the dimer is compared with its associated N,N- and O,N-coordinated mononuclear complexes. The mixed valence complex was prepared electrochemically and a weak inter-valence charge transfer transition is observed which from Hush theory provides an electronic coupling matrix element of 666 cm(-1), suggesting the complex is weakly coupled and valence trapped.