Synopsis of recent research by authors named "Prabuddha Sengupta"
- Prabuddha Sengupta's recent research primarily focuses on the dynamics of viral infection and cellular membrane processes, particularly the mechanisms by which the host cell proteins inhibit HIV-1 infection and the role of membrane microdomains in cellular signaling and protein organization.
- Notable findings include the identification of ZCCHC3 as a novel restriction factor for HIV-1, which blocks both viral production and infection without direct antagonism from viral proteins, demonstrating an important avenue in retroviral research.
- The research also emphasizes advanced imaging techniques, including super-resolution microscopy, to analyze the spatial organization and dynamics of membrane proteins, such as aquaporin-2 and Fas/CD95, thereby contributing to the understanding of cellular responses under various physiological conditions.
