Understanding Bacterial Resistance to Heavy Metals and Nanoparticles: Mechanisms, Implications, and Challenges.

Antimicrobial resistance is a global health problem as it contributes to high mortality rates in several infectious diseases. To address this issue, engineered nanoparticles/nano-formulations of antibiotics have emerged as a promising strategy. Nanoparticles are typically defined as materials with dimensions up to 100 nm and are made of different materials such as inorganic particles, lipids, polymers, etc.

Energy-Efficient and Variability-Resilient 11T SRAM Design Using Data-Aware Read-Write Assist (DARWA) Technique for Low-Power Applications.

The need for power-efficient devices, such as smart sensor nodes, mobile devices, and portable digital gadgets, is markedly increasing and these devices are becoming commonly used in daily life. These devices continue to demand an energy-efficient cache memory designed on Static Random-Access Memory (SRAM) with enhanced speed, performance, and stability to perform on-chip data processing and faster computations. This paper presents an energy-efficient and variability-resilient 11T (EVR11T) SRAM cell, which is designed with a novel Data-Aware Read-Write Assist (DARWA) technique.

Effect of Moringa oleifera leaf extract on exercise and dexamethasone-induced functional impairment in skeletal muscles.

Background: Chronic administration of steroids like dexamethasone produces symptoms including weight loss and skeletal muscle dysfunction. Similar events are reported in chronic or high-intensity exercises, that can lead to fatigue and muscle damage.

Objective: In the present study, the effect of Moringa oleifera leaf extract was evaluated against dexamethasone (Dex) and exercise (Exe)-induced muscle changes in rats.

Machine Learning for Health: Algorithm Auditing & Quality Control.

Developers proposing new machine learning for health (ML4H) tools often pledge to match or even surpass the performance of existing tools, yet the reality is usually more complicated. Reliable deployment of ML4H to the real world is challenging as examples from diabetic retinopathy or Covid-19 screening show. We envision an integrated framework of algorithm auditing and quality control that provides a path towards the effective and reliable application of ML systems in healthcare.

"Triple Trouble" in A Case of Mass Lesion.

Bronchogenic carcinoma, the commonest lung tumor occurs more frequently in the elderly with typical symptoms of cough, haemoptysis, weight loss, dyspnoea or chest pain. These symptoms mimic common respiratory infections in en-demic areas like pulmonary tuberculosis. Also, metastasis at presentation itself is common, the favoured sites being liver, contra-lateral lungs, bones, brain, etc.

Macrodystrophia Lipomatosa: A Single Large Radiological Study of a Rare Entity.

Introduction: We present one of the largest case series of Macrodystrophia lipomatosa, a rare congenital disorder of localized gigantism characterized by overgrowth of all the mesenchymal elements, predominantly involving the fibroadipose tissue.

Aims: To detail the radiological features, pattern of distribution, associated conditions and to suggest an appropriate terminology to describe the condition.

Methods And Material: It is a retrospective study.

Cu-sil dentures - a novel approach to conserve few remaining teeth: Case reports.

The present prime concern in dentistry is on preservation of remaining natural teeth. Presence of few teeth in oral cavity help in preserving alveolar ridge integrity, maintain the proprioception, and gives psychological benefit to the patient. Transitional denture provides us with alternative treatment plan for the patients willing to replace their missing teeth while retaining their very few remaining teeth.

Scorpion sting nephropathy.

Scorpion envenomations are ubiquitous, but nephropathy is a rare manifestation, reported mainly from the Middle East and North Africa. Rapid venom redistribution from blood, delayed excretion from the kidneys, direct toxicity of venom enzymes, cytokine release and afferent arteriolar constriction have been seen in experimental animals. Haemoglobinuria, acute tubular necrosis, interstitial nephritis and haemolytic-uraemic syndrome have been documented in human victims of scorpion envenomation.

Yellow jacket envenomation-related acute renal failure.

We report a 58-year-old man with multiple yellow jacket stings who developed urticaria, renal failure, quadriparesis, rhabdomyolysis in succession. Investigations revealed renal and hepatic dysfunction, proteinuria, demyelinating polyradiculoneuropathy, acute tubular necrosis and glomerulonephritis. He improved with methylprednisolone, antihypertensives and two sessions of haemodialysis.

Stressful life events among adolescents: The development of a new measure.

Background: Adolescence can be a stressful time for children, parents and adults who work with teens. We believe that a scale measuring the events perceived as stressful by an average Indian adolescent is necessary due to the presence of irrelevant items and absence of items related to our culture on foreign scales.

Aim: This study was done to adapt and test the validity of a scale measuring stress caused due to life events in an Indian adolescent; to assess clinical value of the instrument in exploring causal relationships between stressful events and behavioral problems; and to compare the degree of overlap in stress-causing events between adolescents and their parents during the same timeframe.

An improved specimen loader for cryo-scanning electron microscopy.

Cryo-electron microscopy of cryofixed samples is a well-established and accepted technique for imaging liquid-containing specimens without removing water and other volatile components. There are many steps between cryofixation and cryo-observation in the microscope, during which the sample and sample holder need to be handled. One such major step is the loading of the specimen onto the sample holder and the fixing of the sample holder onto the transfer mechanism.

A COMPARISON OF DIFFERENT METHODS OF MEASURING FAT MASS IN HEALTHY INDIANS WITH A WIDE BMI RANGE.

The prediction of fat mass from the measurement of bioelectricai impedance has gained popularity because of the ease of performing the measurement. However, the prediction equation used in this method could be specific for a distribution of body size. This study tested the prediction of fat mass in Indian, by the use of an equation based on bioelectrical impedance, which had earlier been generated on a group of low body mass index (BMI 18.