Diffuse reflectance (DR) spectroscopy is a non-invasive, real-time, and cost-effective tool for early detection of malignant changes in squamous epithelial tissues. The present study aims to evaluate the diagnostic power of diffuse reflectance spectroscopy for non-invasive discrimination of cervical lesions in vivo. A clinical trial was carried out on 48 sites in 34 patients by recording DR spectra using a point-monitoring device with white light illumination.
View Article and Find Full Text PDFObjective: To assess the impact of secondary cytoreduction on survival in our patients with recurrent epithelial ovarian cancer.
Study Design: Between January 2001 and December 2006 all patients who underwent surgical resection of documented epithelial ovarian cancer recurrence were identified from the hospital tumor registry database. Criteria for inclusion were disease-free interval >6 months after completion of primary treatment with clinical and/or radiographic findings suggestive of recurrence.
Objective: To evaluate the effectiveness and safety of the loop electrosurgical excision procedure (LEEP) to treat cervical intraepithelial neoplasia (CIN) in a low-resource setting.
Methods: Women participating in a cervical screening study in India with histologically confirmed CIN unsuitable for cryotherapy were advised to undergo LEEP. One year after treatment the cervix was visually inspected with acetic acid, followed by colposcopy and biopsy taken from abnormal areas.