Publications by authors named "Prabhakaran Rema"

Article Synopsis
  • - Ovarian cysts can sometimes be linked to endocrine disorders, with hypothyroidism being a rare cause that may mimic cancer.
  • - The report discusses three cases of patients mistakenly suspected of having ovarian cancer, but they were actually found to have severe hypothyroidism.
  • - After starting treatment with thyroxine, the patients experienced significant improvement and their ovarian masses resolved, highlighting the importance of considering hypothyroidism in similar cases to prevent unnecessary surgeries.
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Article Synopsis
  • Colposcopy is a diagnostic tool used to evaluate cervical pre-cancer and cancer, with scoring systems that have inconsistencies among different observers, prompting the introduction of the IFCPC nomenclature in 2011 to standardize interpretations.
  • The study aimed to assess the agreement between colposcopic diagnoses using this modified IFCPC terminology and actual cervical pathology, particularly in low-resource settings.
  • Results showed a 65.7% agreement between colposcopic scoring and histopathology, indicating substantial reliability, while agreement with cytology was lower at 35.6%, suggesting the IFCPC terminology enhances colposcopic accuracy compared to traditional methods.
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Diffuse reflectance (DR) spectroscopy is a non-invasive, real-time, and cost-effective tool for early detection of malignant changes in squamous epithelial tissues. The present study aims to evaluate the diagnostic power of diffuse reflectance spectroscopy for non-invasive discrimination of cervical lesions in vivo. A clinical trial was carried out on 48 sites in 34 patients by recording DR spectra using a point-monitoring device with white light illumination.

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Objective: To assess the impact of secondary cytoreduction on survival in our patients with recurrent epithelial ovarian cancer.

Study Design: Between January 2001 and December 2006 all patients who underwent surgical resection of documented epithelial ovarian cancer recurrence were identified from the hospital tumor registry database. Criteria for inclusion were disease-free interval >6 months after completion of primary treatment with clinical and/or radiographic findings suggestive of recurrence.

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Objective: To evaluate the effectiveness and safety of the loop electrosurgical excision procedure (LEEP) to treat cervical intraepithelial neoplasia (CIN) in a low-resource setting.

Methods: Women participating in a cervical screening study in India with histologically confirmed CIN unsuitable for cryotherapy were advised to undergo LEEP. One year after treatment the cervix was visually inspected with acetic acid, followed by colposcopy and biopsy taken from abnormal areas.

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