Effect of Ginkgo biloba Extract on Lead-Induced Oxidative Stress in Different Regions of Rat Brain.

Ginkgo biloba extract (GbE) is a well known natural antioxidant. In the present investigation, its ameliorative effects were tested against lead-induced oxidative stress in rat brain. Four groups of male Wistar rats (100 to 120 g) were used, consisting of eight rats per group.

Attenuation of lead-induced oxidative stress in rat brain, liver, kidney and blood of male Wistar rats by Moringa oleifera seed powder.

Moringa oleifera is a tree belonging to Moringaceae family and its leaves and seeds are reported to have ameliorative effects against metal toxicity. In the present investigation, M. oleifera seed powder was tested against lead-induced oxidative stress and compared against meso-2, 3-dimercaptosuccinic acid (DMSA) treatment.

Carotenoid as a sensitive indicator of sub lethal cadmium toxicity in Penaeus monodon post larvae.

The objective of the present study is to evaluate a sensitive indicator of cadmium by measuring oxygen consumption and carotenoid concentration in post larvae of Penaeus monodon. The post larvae of P. monodon were exposed to 0.

Hydroalcoholic seed extract of Coriandrum sativum (Coriander) alleviates lead-induced oxidative stress in different regions of rat brain.

Lead exposure is known to cause apoptotic neurodegeneration and neurobehavioral abnormalities in developing and adult brain by impairing cognition and memory. Coriandrum sativum is an herb belonging to Umbelliferae and is reported to have a protective effect against lead toxicity. In the present investigation, an attempt has been made to evaluate the protective activity of the hydroalcoholic extract of C.

Ameliorative effects of Bacopa monniera on lead-induced oxidative stress in different regions of rat brain.

Bacopa monniera is a rejuvenating herb for brain cells enhancing learning and cognitive ability. In the present investigation, the ameliorative effects of Bacopa monniera were examined against lead-induced oxidative stress in different regions of rat brain. Male rats were divided into five groups: control (1000 ppm sodium acetate) and exposed (1000 ppm lead acetate) for 4 weeks; DMSA (Meso-2,3-Dimercaptosuccinic acid)-treated (90 mg/kg body weight/day); Bacopa monniera-treated (BM) (10 mg/kg body weight/day) and a combination of BM + DMSA for seven consecutive days after 4 weeks of lead exposure.

Response of glutathione system and carotenoids to sublethal copper in the postlarvae of Penaeus indicus.

The objective of this study is to determine the effect of sublethal copper on the glutathione system and carotenoids of Penaeus indicus postlarvae (PL) when subjected to short- and long-term exposure in the laboratory. The PL were exposed to 0.1641ppm (sublethal) copper for a period of 30 days with sampling intervals of 24, 48, 96h and 10, 20, 30 days.

Influence of lead acetate on glutathione and its related enzymes in different regions of rat brain.

This study is intended to determine the effect of lead acetate on glutathione and its associated enzymes of rat brain. Wistar male rats were treated with lead acetate (500 ppm) through drinking water for a period of 8 weeks and parallel controls were maintained. They were sacrificed at the first, fourth and eighth week to isolate whole brains, which were separated into cerebellum, hippocampus, frontal cortex and brain stem.

Lead-induced increase in antioxidant enzymes and lipid peroxidation products in developing rat brain.

Pregnant rats were treated with 0.4% lead acetate through drinking water from 6th day of gestation and this treatment was continued till 21 post natal days (PND). Four regions of the brain namely hippocampus, cerebellum, frontal cortex and brain stem were dissected at 10, 20, 30 and 40 PND for estimation of lipid peroxidation products (LPP), catalase (CAT) and superoxide dismutase (SOD).

Region specific increase in the antioxidant enzymes and lipid peroxidation products in the brain of rats exposed to lead.

The objective of this study is to determine the effect of lead (pb) on antioxidant enzymes and lipid peroxidation products in different regions of rat brain. Wistar male rats were treated with lead acetate (500 ppm) through drinking water for a period of 8 weeks. Control animals were maintained on sodium acetate.

In vitro effect of lead on Na+, K+-ATPase activity in different regions of adult rat brain.

Lead interferes with cellular energy metabolism by inhibiting ATP (Adenosine triphosphate) synthesis and hydrolysis. This study was conducted to determine in vitro effects of lead on Na+, K+-ATPase activity in four regions of adult rat brain: the cerebellum, the hippocampus, the frontal cortex and the brain stem. Male rats (Wistar strain) weighing 125-150 g were sacrificed, whole brain excised and the four regions were isolated.

Energy levels of Penaeus indicus postlarvae on exposure to lead.

In the present investigation the changes in energy levels or caloric concentrations of Penaeus indicus postlarvae (PL) were determined after exposure to acute and sublethal concen- trations of lead. The biochemical constituents such as carbo- hydrates, proteins, and lipids were estimated in PL exposed to LC(5) (0.1495), LC(10) (0.

Acute toxicity of lead on tolerance, oxygen consumption, ammonia-N excretion, and metal accumulation in Penaeus indicus postlarvae.

The estuaries and backwaters that are the potential breeding grounds of penaeid shrimps are subject to heavy metal pollution through industrial effluents and domestic sewage. In the present investigation, laboratory experiments were conducted to study the acute toxicity of lead on tolerance, oxygen consumption, ammonia-N excretion, and metal accumulation in Penaeus indicus postlarvae. Static bioassay tests were employed to determine tolerance limits.